Maiuri Francesco, Esposito Felice, Del Basso De Caro Marialaura, Tortora Fabio
Department of Neurological Sciences, Section of Neurosurgery, School of Medicine, University Federico II, Naples, Italy.
J Neurooncol. 2003 Jan;61(1):69-72. doi: 10.1023/a:1021258117243.
Malignant oncocytoma of the parotid gland is a quite rare tumor, with only 40 cases with unequivocal histological diagnosis reported in the literature. No cases with intracranial metastasis have been described. The authors report a very unusual case of malignant parotid gland oncocytoma with a large dural extracerebellar metastasis occurring in the contiguous cerebellopontine angle six months after surgery for the primary tumor. Only a partial removal of the dural metastasis was possible because of the cranial nerve and vessel encasement within the mass. Surgery and irradiation resulted in one-year survival. Interestingly, no destruction and infiltration of the petrous and temporal bones were found both at radiological and surgical exploration. We may suggest that metastatic spread from the parotid region to the cerebellopontine angle occurred through the mastoid cells or by haematogenous diffusion through the meningeal branches to the posterior fossa dura from the occipital or ascending pharyngeal arteries.
腮腺恶性嗜酸性细胞瘤是一种非常罕见的肿瘤，文献中仅报道了40例经明确组织学诊断的病例。尚无颅内转移的病例描述。作者报告了一例非常罕见的腮腺恶性嗜酸性细胞瘤病例，在原发性肿瘤手术后6个月，出现了一个位于小脑桥脑角附近的巨大硬脑膜外小脑转移瘤。由于肿块内的颅神经和血管被包裹，仅对硬脑膜转移瘤进行了部分切除。手术和放疗使患者存活了一年。有趣的是，在影像学检查和手术探查中均未发现岩骨和颞骨有破坏和浸润。我们推测，腮腺区域至小脑桥脑角的转移扩散可能是通过乳突细胞，或者是通过枕动脉或咽升动脉的脑膜分支经血液扩散至后颅窝硬脑膜。
