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慢性下腰痛融合手术预后的预测因素。来自瑞典腰椎研究的报告。

Predictors of outcome in fusion surgery for chronic low back pain. A report from the Swedish Lumbar Spine Study.

作者信息

Hägg O, Fritzell P, Ekselius L, Nordwall A

机构信息

Department of Orthopedic Surgery, Sahlgren University Hospital, 413 45 Gothenburg, Sweden.

出版信息

Eur Spine J. 2003 Feb;12(1):22-33. doi: 10.1007/s00586-002-0465-z. Epub 2002 Oct 23.

Abstract

Despite the continuous development of surgical techniques and implants, a substantial number of patients still undergo surgery for chronic low back pain (CLBP) without any benefit, or even become worse. With the aim of finding predictors of functional and work status outcome, 264 patients with severe CLBP of long duration, randomised to surgical or non-surgical treatment, were characterized by socio-demographic, clinical, radiological and psychological variables. The variables were estimated as predictors of outcome at the 2-year follow-up. Univariate and multiple logistic regression analyses were used in both treatment groups. We found that a personality characterized by low neuroticism and low disc height were significant predictors of functional improvement after surgical treatment. Depressive symptoms predicted functional improvement after non-surgical treatment. Work resumption was predicted by low age and short sick leave in the surgical group, and by short sick leave in the non-surgical group. We conclude that improved selection of successful surgical candidates with CLBP seems to be promoted by attention to severe disc degeneration, evaluation of personality traits and shortening of preoperative sick leave.

摘要

尽管手术技术和植入物不断发展,但仍有相当数量的慢性下腰痛(CLBP)患者接受手术后没有任何益处,甚至病情恶化。为了寻找功能和工作状态结果的预测因素,对264例长期严重CLBP患者进行了随机分组,分为手术治疗组和非手术治疗组,并对其社会人口统计学、临床、放射学和心理变量进行了特征分析。这些变量被评估为2年随访结果的预测因素。两个治疗组均采用单因素和多因素Logistic回归分析。我们发现,低神经质人格和椎间盘高度降低是手术治疗后功能改善的重要预测因素。抑郁症状是非手术治疗后功能改善的预测因素。手术组中年龄小和病假短以及非手术组中病假短是恢复工作的预测因素。我们得出结论,关注严重椎间盘退变、评估人格特质和缩短术前病假似乎有助于改善CLBP手术成功候选者的选择。

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