Pestka S, Vince R, LeMahieu R, Weiss F, Fern L, Unowsky J
Antimicrob Agents Chemother. 1976 Jan;9(1):128-30. doi: 10.1128/AAC.9.1.128.
The ability of 53 erythromycin analogues to induce resistance to erythromycin in Staphlococcus aureus was evaluated. Only derivatives with antibacterial activity induced resistance, although some antibacterial compounds did not induce resistance. No derivatives without antibacterial activity but with ability to induce resistance were found.
评估了53种红霉素类似物在金黄色葡萄球菌中诱导对红霉素耐药的能力。只有具有抗菌活性的衍生物能诱导耐药,尽管有些抗菌化合物不能诱导耐药。未发现无抗菌活性但有诱导耐药能力的衍生物。