Dähn U, Hagenmaier H, Höhne H, König W A, Wolf G, Zähner H
Arch Microbiol. 1976 Mar 19;107(2):143-60. doi: 10.1007/BF00446834.
From the fermentation broth of Streptomyces tendae Tü 901 a substance was isolated which inhibits the growth of several fungi. The new antibiotic affects the chitchin biosynthesis. Its structure was identified by mass spectrometry of the products obtained after chemical degradation. Nikkomycin is a nucleoside-peptide antibiotic consisting of uracil, an amino hexuronic acid and a new amino acid containing a pyridin ring.
从灿烂链霉菌Tü 901的发酵液中分离出一种能抑制多种真菌生长的物质。这种新型抗生素影响几丁质的生物合成。通过对化学降解后得到的产物进行质谱分析确定了其结构。多氧霉素是一种核苷肽类抗生素,由尿嘧啶、一种氨基己糖醛酸和一种含吡啶环的新氨基酸组成。