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微生物的代谢产物。第154篇报告。多氧霉素,一种新型的真菌几丁质合成抑制剂。

Stoffwechselprodukte von mikroorganismen. 154. Mitteilung. Nikkomycin, ein neuer hemmstoff der chitinsynthese bei pilzen.

作者信息

Dähn U, Hagenmaier H, Höhne H, König W A, Wolf G, Zähner H

出版信息

Arch Microbiol. 1976 Mar 19;107(2):143-60. doi: 10.1007/BF00446834.

DOI:10.1007/BF00446834
PMID:1259515
Abstract

From the fermentation broth of Streptomyces tendae Tü 901 a substance was isolated which inhibits the growth of several fungi. The new antibiotic affects the chitchin biosynthesis. Its structure was identified by mass spectrometry of the products obtained after chemical degradation. Nikkomycin is a nucleoside-peptide antibiotic consisting of uracil, an amino hexuronic acid and a new amino acid containing a pyridin ring.

摘要

从灿烂链霉菌Tü 901的发酵液中分离出一种能抑制多种真菌生长的物质。这种新型抗生素影响几丁质的生物合成。通过对化学降解后得到的产物进行质谱分析确定了其结构。多氧霉素是一种核苷肽类抗生素,由尿嘧啶、一种氨基己糖醛酸和一种含吡啶环的新氨基酸组成。

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Stoffwechselprodukte von mikroorganismen. 154. Mitteilung. Nikkomycin, ein neuer hemmstoff der chitinsynthese bei pilzen.微生物的代谢产物。第154篇报告。多氧霉素,一种新型的真菌几丁质合成抑制剂。
Arch Microbiol. 1976 Mar 19;107(2):143-60. doi: 10.1007/BF00446834.
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Metabolic products of microorganisms. 252. Isolation of new nikkomycins from Streptomyces tendae.微生物的代谢产物。252. 从天蓝色链霉菌中分离新的多氧霉素
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Nikkomycin Z-Ready to Meet the Promise?尼克霉素Z——准备好兑现承诺了吗?
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