β-熊果酸的抗菌作用。
Antibiotic action of beta-ursolic acid.
作者信息
Kowalewski Z, Kortus M, Kedzia W, Koniar H
出版信息
Arch Immunol Ther Exp (Warsz). 1976;24(1):115-9.
PMID:1259529
Abstract
The antimicrobial action of beta-ursolic acid (triterpenoid sapogenin from the ursan group) has been studied. At the concentration of 300 mug/ml, this substance inhibited growth of all strains of staphylococci investigated. MIC for Gram-positive bacteria ranged between 50 and 500 mug/ml, and 100 to 800 mug/ml for Gram-negative bacteria and yeasts. Acquired resistance to beta-ursolic acid was transient.
摘要
已对β-熊果酸（乌苏烷类三萜皂苷元）的抗菌作用进行了研究。在浓度为300微克/毫升时，该物质抑制了所有所研究葡萄球菌菌株的生长。革兰氏阳性菌的最低抑菌浓度（MIC）在50至500微克/毫升之间，革兰氏阴性菌和酵母菌的MIC则在100至800微克/毫升之间。对β-熊果酸的获得性耐药是短暂的。
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