Ferluga Dusan, Luzar Bostjan, Gadzijev Eldar M
Institute of Pathology, Faculty of Medicine University of Ljubljana, 1000 Ljubljana, Slovenia.
Virchows Arch. 2003 Feb;442(2):136-40. doi: 10.1007/s00428-002-0734-6. Epub 2002 Dec 18.
We report a case of a 63-year-old female, who presented with symptoms and signs of an acute biliary tract obstruction with jaundice and pain. Ultrasound together with intraoperative examination suggested a Klatskin tumour. Following radical resection, a tumour located predominantly in the wall of gallbladder, but infiltrating extensively also the walls of cystic, common hepatic and choledochus duct, was found. On the basis of cell morphology and the results of immunohistochemical analysis, the tumour was classified as an extranodal follicular lymphoma, grade II of the gallbladder, involving also hilar extrahepatic bile ducts. To the best of our knowledge, this is the first report of an extranodal follicular lymphoma in this location. A postoperative follow-up of more than 3 years has been completely uneventful without any symptoms or signs of disease recurrence.
我们报告一例63岁女性患者，其表现出急性胆道梗阻的症状和体征，伴有黄疸和疼痛。超声检查及术中检查提示为肝门部胆管癌。根治性切除术后，发现肿瘤主要位于胆囊壁，但也广泛浸润胆囊管、肝总管和胆总管壁。根据细胞形态学及免疫组化分析结果，该肿瘤被分类为胆囊结外滤泡性淋巴瘤，II级，累及肝门部肝外胆管。据我们所知，这是该部位结外滤泡性淋巴瘤的首例报告。术后超过3年的随访完全无异常，无任何疾病复发的症状或体征。
