Maiga M Y, Dembele M Y, Traoré H A, Kouyate M, Traoré A K, Maiga I I, Bougoudogo F, Doumbo O, Guindo A
Service d'hépato-gastro-entérologie, Hôpital Gabriel Touré, BP 2931 Bamako, Mali.
Bull Soc Pathol Exot. 2002 Nov;95(4):253-6.
Our main objective consists in evaluating the frequency of digestive signs and digestive opportunistic infections in AIDS patients with diarrhea. The prospective study occurred from January 1997 to July 1998 in Bamako hospitals. The patients underwent a clinical examination, blood and stools tests, and sometimes upper digestive endoscopy. Among 434 cases of AIDS, 426 patients (98%) had at least one digestive sign. The main digestive signs were diarrhea (80.1%), abdominal pains (62.2%), vomiting (47.2%) and dysphagea (36.6%). Isospora belli and Cryptosporidium parvum have been pointed up in respectively 9% and 16.3% of examined specimen. Echerichia coli was found in 8.6% of stool cultures and in 2.9% in the case of Salmonella Arizonae. Twenty cases of Kaposi's sarcoma were diagnosed and mycosis was found in 71.9% of patients. In conclusion, digestive change is a constant phenomenon in AIDS patients. Patients survival could be improved by early management, improvement of diagnosis and provisioning of medicines.
我们的主要目标是评估腹泻的艾滋病患者消化系统症状及消化系统机会性感染的发生率。这项前瞻性研究于1997年1月至1998年7月在巴马科的医院开展。患者接受了临床检查、血液和粪便检测,有时还接受了上消化道内镜检查。在434例艾滋病病例中,426例患者(98%)至少有一项消化系统症状。主要的消化系统症状为腹泻(80.1%)、腹痛(62.2%)、呕吐(47.2%)和吞咽困难(36.6%)。在分别9%和16.3%的检测样本中发现了贝氏等孢球虫和微小隐孢子虫。在8.6%的粪便培养物中发现了大肠杆菌,在亚利桑那沙门氏菌感染病例中发现率为2.9%。诊断出20例卡波西肉瘤病例,71.9%的患者发现有真菌病。总之,消化系统改变在艾滋病患者中是一种持续存在的现象。通过早期管理、改善诊断及提供药物可提高患者生存率。