Konate A, Minta D, Diarra M, Dolo A, Dembele M, Diarra B, Maiga M Y, Traore H A, Doumbo O
Service hépato-gastro-entérologie, Hôpital Gabriel Touré, Bamako, Mali.
Bull Soc Pathol Exot. 2005 Apr;98(1):33-5.
The main goal of this work was to study the parasitic infections during AIDS diarrhoea. A longitudinal study was carried out from October 2000 to November 2001 in the Hepato-Gastro-Enterology department of Gabriel Toure Hospital and in the Department of Epidemiology and Parasitic infections of Faculty of Medicine, Pharmacy and Odonto-stomatology of Bamako (Mali), concerning HIV positive patients suffering from diarrhoea. Detecting microbes in stools has been done through direct microscopic examination and according to procedures of Henricksen Poblenz Baerman, Kato Katz and the PCR. Among the 70 patients involved, the sex-ratio was 53%, the average age was 35 +/- 8.4 years. Fever weight loss, skin affections and digestive mycosis were often associated. Opportunistic infections have been relatively frequent with Cryptosporidium parvum with 20%, Isospora belli with 8.5% and Microsporidium with 11.5% of cases. Other non-opportunistic microbes were found. Death within the first two weeks seems more important in case of infection by Cryptosporidium parvum. The frequency and the danger of those opportunistic infections require their efficient diagnosis and care management.
这项工作的主要目标是研究艾滋病腹泻期间的寄生虫感染情况。2000年10月至2001年11月，在加布里埃尔·图雷医院的肝胃肠病科以及马里巴马科医学、药学和口腔医学系的流行病学与寄生虫感染科，针对患有腹泻的HIV阳性患者开展了一项纵向研究。通过直接显微镜检查以及按照亨里克森·波布伦茨·贝尔曼、加藤厚涂片法和聚合酶链反应（PCR）的程序对粪便中的微生物进行检测。在纳入的70名患者中，男女比例为53%，平均年龄为35±8.4岁。发热、体重减轻、皮肤病变和消化道真菌病常同时出现。机会性感染相对常见，其中微小隐孢子虫感染率为20%，贝氏等孢球虫为8.5%，微孢子虫为11.5%。还发现了其他非机会性微生物。微小隐孢子虫感染患者在头两周内的死亡率似乎更高。这些机会性感染的发生率和危险性要求对其进行有效的诊断和治疗管理。
