• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[吗啡中毒病例器官分布的免疫组织化学研究]

[An immunohistochemical study on the distribution in organs in cases with morphine poisoning].

作者信息

Shan Ya-ming, Hao Chun-yu, Wang Long

机构信息

Shenyang Criminal Science and Technology Institute, Shenyang 110002.

出版信息

Fa Yi Xue Za Zhi. 2002 Feb;18(1):9-11.

PMID:12596579
Abstract

OBJECTIVE

To investigate the distribution of mophine in organs in cases with morphine poisioning to select ideal organs for immunohistochemical derection.

METHODS

Localization and half quantitation of morphine in the brain, the kidney, the heart, and the liver were studied in 8 cases with morphine poisoning by immunohistochemical SP method.

RESULTS

Morphine was mainly detected in the cytoplasm of certain parenchymal cells of the organs. The distribution varied greatly with different cases and organs. In the brain and kidney, morphine-positive cells could be easily found.

CONCLUSION

The kidney and brain may be the ideal organs for sampling in suspected morphine poisoning cases with.

摘要

目的

研究吗啡中毒病例中吗啡在各器官中的分布情况,以选择免疫组化检测的理想器官。

方法

采用免疫组化SP法,对8例吗啡中毒患者的脑、肾、心、肝中吗啡进行定位及半定量研究。

结果

吗啡主要在各器官某些实质细胞的胞质中被检测到。不同病例和器官的分布差异很大。在脑和肾中,容易发现吗啡阳性细胞。

结论

对于疑似吗啡中毒病例,肾和脑可能是理想的取材器官。

相似文献

1
[An immunohistochemical study on the distribution in organs in cases with morphine poisoning].[吗啡中毒病例器官分布的免疫组织化学研究]
Fa Yi Xue Za Zhi. 2002 Feb;18(1):9-11.
2
[Distribution of morphine in acute morphine-treated rats].
Hua Xi Yi Ke Da Xue Xue Bao. 1998 Mar;29(1):29-32.
3
Tissue distribution of morphine in the newborns of addicted monkeys and humans. Clinical implications.吗啡在成瘾猴子和人类新生儿中的组织分布。临床意义。
Dev Pharmacol Ther. 1980;1(2-3):163-70.
4
[Postmortem distribution of morphine in rats].
Fa Yi Xue Za Zhi. 1997;13(2):71-2, 74, 128.
5
Distribution of morphine in body fluids and tissues in fatal overdose.致命性过量中毒时吗啡在体液和组织中的分布
J Forensic Sci. 1986 Oct;31(4):1487-91.
6
Morphine concentrations in blood and organs in cases of fatal poisoning.致命中毒病例中血液和器官中的吗啡浓度。
Forensic Sci. 1974 Feb;3(1):77-81. doi: 10.1016/0300-9432(74)90010-7.
7
[Analysis of combined phenothiazine-opiate poisoning].
Arch Kriminol. 1994 Nov-Dec;194(5-6):149-54.
8
[Morphological aspects of diagnosis of acute opiate poisoning].[急性阿片类中毒诊断的形态学方面]
Anesteziol Reanimatol. 2002 Mar-Apr(2):38-42.
9
Effects of morphine dependence and withdrawal on levels of neurosteroids in rat brain.吗啡依赖和戒断对大鼠脑内神经甾体水平的影响。
Acta Pharmacol Sin. 2004 Oct;25(10):1285-91.
10
[Immunohistochemical study on morphine in human tissues from opiate associated death].
Hua Xi Yi Ke Da Xue Xue Bao. 1996 Jun;27(2):151-4.

引用本文的文献

1
Detection of Morphine and Opioids in Fingernails: Immunohistochemical Analysis and Confirmation with Ultra-High-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry.指甲中吗啡和阿片类物质的检测:免疫组织化学分析及超高效液相色谱-高分辨率质谱联用确证
Toxics. 2022 Jul 26;10(8):420. doi: 10.3390/toxics10080420.