Shan Ya-ming, Hao Chun-yu, Wang Long
Shenyang Criminal Science and Technology Institute, Shenyang 110002.
Fa Yi Xue Za Zhi. 2002 Feb;18(1):9-11.
To investigate the distribution of mophine in organs in cases with morphine poisioning to select ideal organs for immunohistochemical derection.
Localization and half quantitation of morphine in the brain, the kidney, the heart, and the liver were studied in 8 cases with morphine poisoning by immunohistochemical SP method.
Morphine was mainly detected in the cytoplasm of certain parenchymal cells of the organs. The distribution varied greatly with different cases and organs. In the brain and kidney, morphine-positive cells could be easily found.
The kidney and brain may be the ideal organs for sampling in suspected morphine poisoning cases with.
研究吗啡中毒病例中吗啡在各器官中的分布情况,以选择免疫组化检测的理想器官。
采用免疫组化SP法,对8例吗啡中毒患者的脑、肾、心、肝中吗啡进行定位及半定量研究。
吗啡主要在各器官某些实质细胞的胞质中被检测到。不同病例和器官的分布差异很大。在脑和肾中,容易发现吗啡阳性细胞。
对于疑似吗啡中毒病例,肾和脑可能是理想的取材器官。