Shima Hidehiro, Nishizaki Takafumi, Ishihara Hideyuki, Moroi Junta, Fujii Masami, Suzuki Michiyasu
Department of Neurosurgery, Yamaguchi University School of Medicine, Yamaguchi, Japan.
J Clin Neurosci. 2002 Nov;9(6):708-10. doi: 10.1054/jocn.2001.1068.
Most recurrences of intracranial pure germinoma occur at the primary site, ventricular wall or subarachnoid space. We report a rare case of intracranial germinoma that recurred along the shunt tube 17 years after prior ventriculoperitoneal shunt and radiotherapy. The recurrent tumor, verified histologically as a pure germinoma, involved the right frontal lobe along the ventricular catheter. In spite of subsequent surgery, radiation and chemotherapy, the tumor recurred repeatedly. Recurrence after such a long period highlights the necessity of long-term follow up for patients with germinoma. We also discuss possible causes of tumor dissemination along the ventricular catheter.
颅内纯生殖细胞瘤的大多数复发发生在原发部位、脑室壁或蛛网膜下腔。我们报告1例罕见的颅内生殖细胞瘤，在既往脑室腹腔分流术和放疗17年后沿分流管复发。复发性肿瘤经组织学证实为纯生殖细胞瘤，沿脑室导管累及右额叶。尽管随后进行了手术、放疗和化疗，但肿瘤仍反复复发。如此长时间后的复发凸显了对生殖细胞瘤患者进行长期随访的必要性。我们还讨论了肿瘤沿脑室导管播散的可能原因。
