福司曲星的形式催化不对称全合成。
Formal catalytic asymmetric total synthesis of fostriecin.
作者信息
Fujii Kunihiko, Maki Keisuke, Kanai Motomu, Shibasaki Masakatsu
机构信息
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
出版信息
Org Lett. 2003 Mar 6;5(5):733-6. doi: 10.1021/ol027528o.
PMID:12605502
Abstract
The common synthetic intermediate of a potent and promising anticancer agent, fostriecin, was synthesized using a unique method that combines four catalytic asymmetric reactions as shown above.
摘要
一种强效且有前景的抗癌药物福司曲星的常见合成中间体，是采用一种独特方法合成的，该方法结合了上述四种催化不对称反应。
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