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[足部骨骼肿瘤——汉堡骨肿瘤登记处的报告]

[Tumors of the footbones- a report from the Hamburg Bone Tumor Registry].

作者信息

Pollandt K, Werner M, Delling G

机构信息

Institut für Osteopathologie, Zentrum für klinisch-theoretische Medizin I, Universitätsklinikum Hamburg-Eppendorf, Germany.

出版信息

Z Orthop Ihre Grenzgeb. 2003 Jul-Aug;141(4):445-51. doi: 10.1055/s-2003-41570.

Abstract

Aim of the present study was a systematic examination of the tumors of the foot registered in the Hamburg Bone Tumor Registry regarding age, sex, location, diagnosis and morphological characteristics. The registry files and histological specimens of 367 tumors and tumor-like lesions of the foot were reviewed. Males were more frequently affected (ratio 4 : 3). Some 20.4 % of all mass forming tumors were malignant. Cartilage tumors (146 cases), cystic (132 cases) and osteoblastic lesions (33 cases) were most common. Several tumors showed a strong predilection for certain parts of the foot. In the calcaneus a solitary bone cyst was the most common lesion. Lesions in the talus and metatarsals with a similar morphology mostly represented intraosseous ganglion cysts. Other tumors in the calcaneus were mainly cartilaginous. Besides chondroblastoma, chondrosarcoma was regularly diagnosed. Chondroma was extremely rare at this site. Contrary to that chondroma was regularly found at the metatarsal and phalangeal bones, it was 4 times more common than chondrosarcoma. An even distribution showed aneurysmal bone cysts and osteoidosteoma. Very rare lesions were fibrous dysplasia, eosinophilic granuloma and intraosseous lipoma. The knowledge of the distribution of tumors in the foot is important for an exact differential diagnosis and thereby for biopsy planning, diagnosis and therapy.

摘要

本研究的目的是对汉堡骨肿瘤登记处登记的足部肿瘤进行系统检查,内容涉及年龄、性别、位置、诊断及形态学特征。回顾了登记处档案以及367例足部肿瘤和肿瘤样病变的组织学标本。男性受累更为常见(比例为4∶3)。所有形成肿块的肿瘤中约20.4%为恶性。软骨肿瘤(146例)、囊性病变(132例)和成骨病变(33例)最为常见。几种肿瘤对足部某些部位有明显的偏好。跟骨中最常见的病变是孤立性骨囊肿。距骨和跖骨中形态相似的病变大多为骨内腱鞘囊肿。跟骨中的其他肿瘤主要为软骨性肿瘤。除了成软骨细胞瘤外,经常诊断出软骨肉瘤。软骨瘤在该部位极为罕见。与此相反,软骨瘤在跖骨和趾骨中经常出现,其发生率比软骨肉瘤高4倍。动脉瘤样骨囊肿和骨样骨瘤分布均匀。纤维发育不良、嗜酸性肉芽肿和骨内脂肪瘤是非常罕见的病变。了解足部肿瘤的分布情况对于准确的鉴别诊断以及活检计划制定、诊断和治疗都很重要。

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