Zhang D L, Jiang Z W, Jiang J, Cao B, Li J S
Research Institute of General Surgery, School of Medicine, Nanjing University, Peoples Republic of China.
Postgrad Med J. 2003 Feb;79(928):110-2. doi: 10.1136/pmj.79.928.110.
A 12 year old boy presented with 11 episodes of weakness, ataxia, nausea, slurred speech, dehydration, and sometimes severe lethargy bordering on coma. A year previously the boy had small intestinal resections leaving 20 cm of small bowel remaining. D-lactic acidosis was diagnosed on the basis of a D-lactate level of 5.23 mmol/l. The clinical presentation of the disease is recurrent episodes of unusual neurological manifestations and severe metabolic acidosis. The diagnosis is dependent on the presentations and the plasma D-lactate level. Development of the syndrome seems to be the effect of the accumulation of D-lactic acid.
一名12岁男孩出现11次虚弱、共济失调、恶心、言语不清、脱水症状，有时还会出现接近昏迷的严重嗜睡。一年前，该男孩进行了小肠切除术，剩余20厘米小肠。根据D-乳酸水平为5.23毫摩尔/升，诊断为D-乳酸性酸中毒。该病的临床表现为反复出现异常神经表现和严重代谢性酸中毒。诊断取决于临床表现和血浆D-乳酸水平。该综合征的发生似乎是D-乳酸积累的结果。
