Johnson Karl, Haigh S Fiona, Ehtisham Sarah, Ryder Clive, Gardner-Medwin Janet
Department of Radiology, Birmingham Children's Hospital NHS Trust, Steelhouse Lane, UK.
Pediatr Radiol. 2003 Mar;33(3):194-9. doi: 10.1007/s00247-002-0853-x. Epub 2002 Dec 20.
Childhood idiopathic chondrolysis of the hip (ICH) causes progressive destruction of the articular cartilage of the hip joint with associated bone remodelling. The MRI features of this disease have not previously been described.
To document the MRI features of childhood ICH and determine which features may help distinguish ICH from other causes of hip joint destruction in the paediatric population.
A retrospective review of the MRI examinations of children with clinically diagnosed ICH. All children had undergone synovial biopsy and/or joint aspiration with plain hip radiography to exclude causes of secondary chondrolysis.
Ten MRI examinations were performed on six children. Cartilage loss, small hip joint effusions, bone remodelling and significant regional muscle wasting were seen in all children. Cartilage loss was most severe in the central part of the joint. Synovial enhancement was not a constant feature of ICH. Serial imaging in three children showed disease progression.
MRI in ICH clearly demonstrates cartilage loss and enables delineation of bone and muscle abnormalities. It is helpful in the differential diagnosis of hip joint disease in children and may provide further information on the progression and aetiology of ICH.
儿童髋关节特发性软骨溶解症(ICH)会导致髋关节软骨进行性破坏并伴有骨重塑。此前尚未描述过该疾病的MRI特征。
记录儿童ICH的MRI特征,并确定哪些特征有助于将ICH与儿科人群中髋关节破坏的其他原因区分开来。
对临床诊断为ICH的儿童的MRI检查进行回顾性分析。所有儿童均接受了滑膜活检和/或关节穿刺,并进行了髋关节X线平片检查以排除继发性软骨溶解的原因。
对6名儿童进行了10次MRI检查。所有儿童均可见软骨丢失、髋关节少量积液、骨重塑和明显的局部肌肉萎缩。软骨丢失在关节中部最为严重。滑膜强化并非ICH的恒定特征。对3名儿童的系列成像显示疾病进展。
ICH的MRI清楚地显示了软骨丢失,并能够描绘骨和肌肉异常。它有助于儿童髋关节疾病的鉴别诊断,并可能提供有关ICH进展和病因的进一步信息。