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免疫抑制疗法和关节镜干预治疗特发性髋关节溶解症

Idiopathic Chondrolysis of the Hip Treated by Immunosuppressive Therapy and Arthroscopic Intervention.

作者信息

Endo Hirosuke, Akazawa Hirofumi, Yashiro Masato, Yamada Kazuki, Sanki Tomoaki, Tetsunaga Tomonori, Nishida Keiichiro, Furumatsu Takayuki, Ozaki Toshifumi

机构信息

Department of Orthopaedic Surgery, Okayama Rosai Hospital, Okayama 702-8055,

Department of Orthopaedic Surgery, Asahigawaso Rehabilitation and Medical Center, Okayama 703-8555, Japan.

出版信息

Acta Med Okayama. 2020 Feb;74(1):77-81. doi: 10.18926/AMO/57957.

DOI:10.18926/AMO/57957
PMID:32099253
Abstract

Idiopathic chondrolysis of the hip (ICH), a very rare disorder of unknown etiology, occurs mainly in female adolescents. Characterized by pain, limp, stiffness and radiological narrowing joint space from the rapid destruction of the articular cartilage, ICH sometimes results in ankyloses. We present the case of a 10-year-old girl diagnosed with ICH based on arthroscopic inspection and synovium biopsy. The femoral deformity appeared gradually, like a cam-type femoroacetabular impingement. She was treated with intensive rehabilitation and immunosuppressive drug. We later performed an arthroscopic bumpectomy for residual symptoms. She achieved a favorable outcome as a 15-year-old at the latest follow-up.

摘要

髋关节特发性软骨溶解症(ICH)是一种病因不明的极为罕见的病症,主要发生在青春期女性。其特征为疼痛、跛行、关节僵硬以及因关节软骨迅速破坏导致的影像学上关节间隙变窄,ICH有时会导致关节强直。我们报告一例10岁女孩的病例,该病例经关节镜检查和滑膜活检确诊为ICH。股骨畸形逐渐出现,类似凸轮型股骨髋臼撞击症。她接受了强化康复治疗和免疫抑制药物治疗。后来,针对残留症状我们为她实施了关节镜下骨赘切除术。在最近一次随访时,她15岁,取得了良好的治疗效果。

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引用本文的文献

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Idiopathic Chondrolysis of the Hip in Adolescents: Updated Evidence for Clinical Management.青少年髋关节特发性软骨溶解症:临床管理的最新证据
J Pediatr Soc North Am. 2025 Mar 26;11:100187. doi: 10.1016/j.jposna.2025.100187. eCollection 2025 May.
2
Minimally invasive treatment for idiopathic chondrolysis of the hip: analysis of forty-one cases.微创治疗特发性髋关节软骨溶解症:41 例分析。
Int Orthop. 2024 Jun;48(6):1627-1634. doi: 10.1007/s00264-024-06137-0. Epub 2024 Mar 19.
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Idiopathic Chondrolysis of the Hip in Two Adolescent Females: A Six-Year Follow-Up.
两名青春期女性髋关节特发性软骨溶解症:六年随访
Cureus. 2023 May 19;15(5):e39233. doi: 10.7759/cureus.39233. eCollection 2023 May.
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MRI Features and Treatment for Idiopathic Chondrolysis of the Hip (ICH) in Children: Outcomes of a Systematic Review.儿童髋关节特发性软骨溶解症(ICH)的MRI特征及治疗:一项系统评价的结果
Indian J Orthop. 2022 Jul 2;56(9):1491-1505. doi: 10.1007/s43465-022-00684-7. eCollection 2022 Sep.