Ruiz Picazo David, Doñate Pérez Francisco, Jiménez Ortega Plácido, Gaspar Aparicio Natalia
Department of Pediatric Orthopaedics Surgery, University Hospital of Albacete, Albacete, Spain.
J Pediatr Orthop B. 2016 Nov;25(6):533-8. doi: 10.1097/BPB.0000000000000347.
Idiopathic chondrolysis of the hip (ICH) is a rare condition of unknown etiology, and is characterized by rapid, progressive destruction of the articular cartilage in the coxofemoral joint. This condition has an insidious onset, and is observed more commonly in female preadolescents. Patients report intense pain, motion restriction, and often present with an antalgic gait. Medical imaging techniques are required to make a differential diagnosis and biological markers for inflammation and infection should be evaluated. Avascular necrosis, septic arthritis, and juvenile idiopathic arthritis are the primary alternatives that should be precluded before making a diagnosis. Conservative treatment focuses on pain control and preservation of joint mobility. However, surgical treatment may be an option for these patients. We present a rare case of a 10-year-old boy where imaging tests and physical examination were consistent with conventional idiopathic hip chondrolysis. Following hip joint biopsy and culture, we observed the presence of bacteria originating from the mouth, which could have been responsible for the pathogenesis of ICH. This is the first report of ICH in which common bacteria of the mouth were found upon joint biopsy. In addition, with respect to the pathogenesis of hip chondrolysis, this case emphasizes that numerous factors are involved, many of which remain unknown.
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髋关节特发性软骨溶解症(ICH)是一种病因不明的罕见病症,其特征是髋股关节的关节软骨迅速、进行性破坏。这种病症起病隐匿,在青春期前女性中更为常见。患者报告有剧痛、活动受限,且常表现为痛性步态。需要医学成像技术进行鉴别诊断,并且应评估炎症和感染的生物标志物。在做出诊断之前,应排除主要的鉴别诊断,如缺血性坏死、化脓性关节炎和幼年特发性关节炎。保守治疗侧重于疼痛控制和关节活动度的保留。然而,手术治疗可能是这些患者的一种选择。我们报告一例罕见的10岁男孩病例,其影像学检查和体格检查与传统的特发性髋关节软骨溶解症相符。在进行髋关节活检和培养后,我们观察到存在源自口腔的细菌,这可能是ICH发病机制的原因。这是首次在关节活检时发现口腔常见细菌的ICH报告。此外,关于髋关节软骨溶解症的发病机制,该病例强调涉及众多因素,其中许多因素仍不清楚。
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