Bleck E E
J Bone Joint Surg Am. 1983 Dec;65(9):1266-75.
The cases of nine patients (eleven hips) with idiopathic chondrolysis of the hip were studied. Seven of the patients were white and two were Hispanic. The age at onset ranged from eight to sixteen years (mean, 11.5 years). Four patients were boys and five were girls. All patients had a decreased passive range of motion of the hip, and radiographic examination showed regional osteoporosis, premature closure of the femoral capital physis, narrowing of the joint space, and lateral overgrowth of the femoral head on the neck. All laboratory examinations were negative for evidence of infection or rheumatoid arthritis. An arthrotomy was done in seven patients. Specimens of the synovial tissue showed no growth on culture, and the histological studies revealed only minimum signs of inflammation. Histological studies of the articular cartilage were normal. Treatment consisted of administration of acetylsalicylic acid in therapeutic dosages to maintain a blood salicylate level of fifteen to twenty-five milligrams per cent, active non-loading exercise of the hip, protected weight-bearing with crutches, short-term traction to overcome or relieve contractures after biopsy, iliopsoas tenotomy or lengthening in three patients, and an adductor myotomy in one patient. At follow-up, 2.3 to 9.4 years after onset (mean, 6.2 years), six patients had either no symptoms or only minor intermittent discomfort in the hip. On radiographic examination, although these six patients had restoration of the joint space they did have lateral overgrowth of the femoral head (lateral buttressing) and overgrowth of the lateral acetabular margin (lateral osteophyte). In three patients who had disabling pain, joint deterioration was evident on the radiographic examination. One of these patients had a resurfacing arthroplasty to relieve pain.
对9例(11髋)特发性髋关节溶解症患者的病例进行了研究。其中7例患者为白人,2例为西班牙裔。发病年龄在8至16岁之间(平均11.5岁)。4例为男孩,5例为女孩。所有患者髋关节的被动活动范围均减小,影像学检查显示局部骨质疏松、股骨头骨骺过早闭合、关节间隙变窄以及股骨头颈部外侧过度生长。所有实验室检查均未发现感染或类风湿关节炎的证据。7例患者接受了关节切开术。滑膜组织标本培养无生长,组织学研究仅显示轻微炎症迹象。关节软骨的组织学研究正常。治疗包括给予治疗剂量的乙酰水杨酸以维持血水杨酸水平在每百毫升15至25毫克,进行髋关节主动非负重锻炼,使用拐杖进行保护性负重,活检后短期牵引以克服或缓解挛缩,3例患者进行髂腰肌切断术或延长术,1例患者进行内收肌切断术。随访时,发病后2.3至9.4年(平均6.2年),6例患者髋关节无症状或仅有轻微间歇性不适。影像学检查显示,尽管这6例患者关节间隙已恢复,但股骨头仍有外侧过度生长(外侧支撑)和髋臼外侧边缘过度生长(外侧骨赘)。3例有严重疼痛的患者影像学检查显示关节恶化。其中1例患者接受了表面置换关节成形术以缓解疼痛。