糖尿病患者的压力反射敏感性及对瓦尔萨尔瓦动作的反应
Baroreflex sensitivity and responses to the Valsalva manoeuvre in subjects with diabetes mellitus.
作者信息
Bennett T, Hosking D J, Hampton J R
出版信息
J Neurol Neurosurg Psychiatry. 1976 Feb;39(2):178-83. doi: 10.1136/jnnp.39.2.178.
Abstract
Baroreflex sensitivity was measured in a group of diabetic patients from the slope of the regression of pulse interval on systolic arterial pressure, during elevation of pressure induced by phenylephrine. The response to Valsalva's manoeuvre was assessed in the same subjects. There was a good correlation between the two tests in the identification of patients with a parasympathetic autonomic disturbance, but measurements of baroreflex sensitivity were more readily quantifiable than were the responses to Valsalva's manoeuvre. Furthermore, baroreflex sensitivity could be measured in patients with sympathetic nervous dysfunction in whom vagal function could not be assessed by means of the Valsalva manoeuvre. Measurement of baroreflex sensitivity is likely to be suitable for longitudinal studies of the progress of diabetic autonomic neuropathy.
摘要
在一组糖尿病患者中，通过在去氧肾上腺素引起的血压升高期间，测量脉搏间期与收缩期动脉压回归曲线的斜率来测定压力反射敏感性。在同一组受试者中评估了对瓦尔萨尔瓦动作的反应。在识别副交感神经自主神经功能障碍患者时，这两种测试之间存在良好的相关性，但压力反射敏感性的测量比瓦尔萨尔瓦动作的反应更容易量化。此外，对于交感神经功能障碍且无法通过瓦尔萨尔瓦动作评估迷走神经功能的患者，可以测量压力反射敏感性。压力反射敏感性的测量可能适用于糖尿病自主神经病变进展的纵向研究。
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