Myklebust Geirmund, Wilsgaard Tom, Jacobsen Bjarne Koster, Gran Jan Tore
Department of Rheumatology, Institute of Clinical Medicine, University of Tromsø, Tromsø, Norway.
Scand J Rheumatol. 2003;32(1):38-41. doi: 10.1080/03009740310000382.
To determine causes of death in patients with pure polymyalgia rheumatica (PMR) compared to matched population controls.
In a population based study from 1987-1997, 315 patients were diagnosed with PMR. The patients were each randomly assigned four population controls, totally 1,260 controls. The date and causes of death were identified from the data files at Statistics Norway up to the end of 1997.
A total of 65 cases (20.6%) with PMR died compared to 338 (26.8%) among the controls (mortality rate ratio (MRR) = 0.73, 95% CI 0.56-0.97, p = 0.03). No statistically significant difference was found between patients and controls with regard to mortality from coronary heart disease or stroke (MRR=0.78, 95% CI 0.52-1.18), cancer (MRR = 0.59, 95% CI 0.30-1.17), and other causes (MRR=0.75, 95% CI 0.48-1.17).
The increased survival found in patients with PMR could not be explained by reduction in any particular cause of death.
确定与匹配的人群对照相比，单纯性风湿性多肌痛（PMR）患者的死亡原因。
在一项基于1987 - 1997年人群的研究中，315例患者被诊断为PMR。每位患者被随机分配4名人群对照，共1260名对照。从挪威统计局的数据文件中确定截至1997年底的死亡日期和原因。
共有65例（20.6%）PMR患者死亡，而对照中有338例（26.8%）死亡（死亡率比（MRR）= 0.73，95%置信区间0.56 - 0.97，p = 0.03）。在冠心病或中风死亡率（MRR = 0.78，95%置信区间0.52 - 1.18）、癌症（MRR = 0.59，95%置信区间0.30 - 1.17）以及其他原因（MRR = 0.75，95%置信区间0.48 - 1.17）方面，患者与对照之间未发现统计学上的显著差异。
PMR患者生存率的提高无法用任何特定死亡原因的减少来解释。
