Vatassery G T, Berry J F, Younozai R, Lam Bergad P
Lipids. 1976 Apr;11(4):317-21. doi: 10.1007/BF02544060.
Three-week old male Sprague-Dawley rats were placed on a control or vitamin E-deficient diet for 9 months. The total lipid and cholesterol contents of brain gray and white matter areas in the vitamin E-deficient group did not differ from controls. The concentration of cerebrosides was lower in white matter but higher in gray matter of deficient animals. However, sulfatide was significantly (P less than 0.001) higher in white and gray matter of deficient animals compared with controls. Lysolecithin was not found in vitamin E-deficient gray matter but was present in control gray matter lipids. No marked differences were found in the concentrations or relative amounts of sphingomyelin, phosphatidyl choline, phosphatidyl ethanolamine, phosphatidyl serine, or phosphatidyl inositol in the phospholipids of gray or white matter of vitamin E-deficient rats as compared to controls. In addition, no remarkable differences were found in the fatty acid composition of total lipid extracts of gray or white matter from vitamin E-deficient rats when compared with controls.
将三周龄的雄性斯普拉格-道利大鼠置于对照饮食或维生素E缺乏饮食中9个月。维生素E缺乏组脑灰质和白质区域的总脂质和胆固醇含量与对照组无差异。缺乏维生素E的动物白质中脑苷脂浓度较低，而灰质中较高。然而，与对照组相比，缺乏维生素E的动物白质和灰质中的硫脂显著升高（P小于0.001）。在维生素E缺乏的灰质中未发现溶血卵磷脂，但在对照灰质脂质中存在。与对照组相比，维生素E缺乏大鼠灰质或白质磷脂中的鞘磷脂、磷脂酰胆碱、磷脂酰乙醇胺、磷脂酰丝氨酸或磷脂酰肌醇的浓度或相对含量没有显著差异。此外，与对照组相比，维生素E缺乏大鼠灰质或白质总脂质提取物的脂肪酸组成没有显著差异。
