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糖尿病合并高血压患者的心血管危险因素

Cardiovascular risk factors in diabetic patients with hypertension.

作者信息

Winer Nathaniel, Sowers James R

机构信息

Department of Medicine, SUNY Health Science Center, 450 Clarkson Avenue, Box 1205, Brooklyn, NY 11203, USA.

出版信息

Curr Diab Rep. 2002 Jun;2(3):263-6. doi: 10.1007/s11892-002-0093-3.

Abstract

Individuals with diabetes mellitus have cardiovascular disease (CVD) mortality comparable to nondiabetics who have suffered a myocardial infarction or stroke. Aggressive management of risk factors such as hypertension, dyslipidemia, and platelet dysfunction in persons with diabetes has been shown to reduce morbidity and mortality in prospective randomized controlled clinical trials. Accordingly, there are national mandates to lower blood pressure to less than 130/85 mm Hg, reduce low-density lipoprotein cholesterol to less than 100 mg/dL, and institute aspirin therapy in adult patients with diabetes. Although not definitively shown to reduce CVD, there are also recommendations to control the level of glycemia, as well. This article discusses CVD risk factors in the diabetic patient with hypertension.

摘要

糖尿病患者的心血管疾病(CVD)死亡率与曾患心肌梗死或中风的非糖尿病患者相当。在前瞻性随机对照临床试验中,积极管理糖尿病患者的高血压、血脂异常和血小板功能等风险因素已显示可降低发病率和死亡率。因此,国家规定将糖尿病成年患者的血压降至130/85 mmHg以下,将低密度脂蛋白胆固醇降至100 mg/dL以下,并采用阿司匹林治疗。虽然尚未明确显示控制血糖水平可降低心血管疾病风险,但也有相关建议。本文讨论了合并高血压的糖尿病患者的心血管疾病风险因素。

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