吸烟对肌肉骨骼相关残疾的影响。
The effect of cigarette smoking on musculoskeletal-related disability.
作者信息
Lincoln Andrew E, Smith Gordon S, Amoroso Paul J, Bell Nicole S
机构信息
War-Related Illness and Injury Study Center, Veterans Affairs Medical Center, Washington DC 20422, USA.
出版信息
Am J Ind Med. 2003 Apr;43(4):337-49. doi: 10.1002/ajim.10195.
BACKGROUND
This study describes cigarette smoking's effect on development of physical disability following initial musculoskeletal-related hospitalization.
METHODS
We followed 15,140 US Army personnel hospitalized for common musculoskeletal disorders between 1989-1996 for up to 8 years (1997) to assess risk for long-term physical disability.
RESULTS
Trends between increased smoking level and long-term disability were identified for persons with knee injuries, rotator cuff injuries, and intervertebral disc displacement. In proportional hazards models, disability was significantly associated with heavy smoking among all subjects (relative hazard (RH) = 1.21). Both heavy smokers (RH = 1.49) and light to moderate smokers (RH = 1.44) were at greater risk for disability following meniscal injuries. Excess fraction due to smoking among subjects with meniscal injuries who currently smoke was 38%.
CONCLUSIONS
Findings suggest an association between smoking and development of disability following meniscal injury. Given the high excess fraction of disability associated with smoking, other studies are needed to confirm this association.
背景
本研究描述了吸烟对首次因肌肉骨骼相关疾病住院后身体残疾发展的影响。
方法
我们对1989年至1996年间因常见肌肉骨骼疾病住院的15140名美国陆军人员进行了长达8年（至1997年）的随访，以评估长期身体残疾的风险。
结果
在膝部损伤、肩袖损伤和椎间盘移位患者中，发现吸烟水平升高与长期残疾之间存在趋势。在比例风险模型中，所有受试者的残疾与重度吸烟显著相关（相对风险（RH）=1.21）。半月板损伤后，重度吸烟者（RH = 1.49）和轻度至中度吸烟者（RH = 1.44）的残疾风险均更高。目前吸烟的半月板损伤受试者中，吸烟导致的超额发病率为38%。
结论
研究结果表明吸烟与半月板损伤后残疾的发展之间存在关联。鉴于与吸烟相关的残疾超额发病率较高，需要其他研究来证实这种关联。
Zotero 插件