Neumann C G, Alpaugh M
Pediatrics. 1976 Apr;57(4):469-73.
Infant birthweight doubling time is widely quoted as being achieved between 5 and 6 months. The purpose of this study was to determine the time of birthweight doubling and to identify important related variables. A total of 357 normal infants with birthweights between 2,500 and 4,100 gm were studied. Mean age of birthweight doubling for the entire group was 119 days (3.8 months). Bottle-fed infants doubled their birthweights earlier than breast-fed infants: 113 days vs. 124 days (P less than .05). Boys doubled their birthweights earlier than girls: 111 days vs. 129 days (P less than .0001). Solids were introduced earlier in bottle-fed infants (mean , 1.9 months) than in breast-fed infants (mean, 3.9 months). Harvard percentiles for mean group weight and length at the time of birthweight doubling were: for bottle-fed infants, 75th and 55th percentiles respectively: for breast-fed infants, 55th and 60th percentiles respectively; for boys, 75th percentile for both weight and length; for girls, 50th percentile for both weight and length. Thus, bottle-fed infants appear to have weight gains in excess of length gain and may be developing early obesity. In light of the poor prognosis in treating obesity, closer supervision of early infant feeding practices is indicated.
婴儿出生体重翻倍的时间普遍认为是在5到6个月之间。本研究的目的是确定出生体重翻倍的时间，并找出重要的相关变量。共对357名出生体重在2500克至4100克之间的正常婴儿进行了研究。整个组出生体重翻倍的平均年龄为119天（3.8个月）。人工喂养的婴儿出生体重翻倍的时间比母乳喂养的婴儿早：113天对124天（P<0.05）。男孩出生体重翻倍的时间比女孩早：111天对129天（P<0.0001）。人工喂养的婴儿比母乳喂养的婴儿更早开始添加固体食物（平均分别为1.9个月和3.9个月）。出生体重翻倍时，该组婴儿平均体重和身长的哈佛百分位数分别为：人工喂养的婴儿体重为第75百分位数，身长为第55百分位数；母乳喂养的婴儿体重为第55百分位数，身长为第60百分位数；男孩体重和身长均为第75百分位数；女孩体重和身长均为第50百分位数。因此，人工喂养的婴儿似乎体重增加超过身长增加，可能正在早期肥胖。鉴于治疗肥胖的预后较差，需要对婴儿早期喂养方式进行更密切的监督。
