Wise L, Stein T
Surg Gynecol Obstet. 1976 May;142(5):686-8.
Certain aspects of the pathogenesis of the diarrhea after bypass procedures of the small intestine for obesity have been evaluated. In the late postoperative period, a significant increase occurred in fecal weight and in fecal bile salt and free fatty acid output. There was a significant direct correlation between fecal weight and fecal bile salt output. There was no significant correlation between fecal weight and fecal fatty acid output. This suggests that, after bypass procedures of the small intestine, bile salts play a more significant role in the pathogenesis of diarrhea than do free fatty acids.
小肠旁路手术治疗肥胖后腹泻的发病机制的某些方面已得到评估。在术后晚期,粪便重量、粪便胆汁盐和游离脂肪酸排出量显著增加。粪便重量与粪便胆汁盐排出量之间存在显著的直接相关性。粪便重量与粪便脂肪酸排出量之间无显著相关性。这表明,小肠旁路手术后,胆汁盐在腹泻发病机制中比游离脂肪酸起更重要的作用。