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小肠旁路术后腹泻的发病机制。

The pathogenesis of diarrhea after bypass of the small intestine.

作者信息

Wise L, Stein T

出版信息

Surg Gynecol Obstet. 1976 May;142(5):686-8.

PMID:1265608
Abstract

Certain aspects of the pathogenesis of the diarrhea after bypass procedures of the small intestine for obesity have been evaluated. In the late postoperative period, a significant increase occurred in fecal weight and in fecal bile salt and free fatty acid output. There was a significant direct correlation between fecal weight and fecal bile salt output. There was no significant correlation between fecal weight and fecal fatty acid output. This suggests that, after bypass procedures of the small intestine, bile salts play a more significant role in the pathogenesis of diarrhea than do free fatty acids.

摘要

小肠旁路手术治疗肥胖后腹泻的发病机制的某些方面已得到评估。在术后晚期,粪便重量、粪便胆汁盐和游离脂肪酸排出量显著增加。粪便重量与粪便胆汁盐排出量之间存在显著的直接相关性。粪便重量与粪便脂肪酸排出量之间无显著相关性。这表明,小肠旁路手术后,胆汁盐在腹泻发病机制中比游离脂肪酸起更重要的作用。

相似文献

1
The pathogenesis of diarrhea after bypass of the small intestine.小肠旁路术后腹泻的发病机制。
Surg Gynecol Obstet. 1976 May;142(5):686-8.
2
Gastric emptying and bile acid concentration in the duodenum after bypass operation of the small intestine because of obesity.
Scand J Gastroenterol. 1976;11(2):151-4.
3
Role of the small intestine in postvagotomy diarrhea.小肠在迷走神经切断术后腹泻中的作用。
Gastroenterology. 1983 Nov;85(5):1088-93.
4
Fecal excretion of bile acids: a new technique for studying bile acid kinetics in patients with ileal resection.胆汁酸的粪便排泄:一种研究回肠切除患者胆汁酸动力学的新技术。
J Clin Invest. 1971 Dec;50(12):2531-40. doi: 10.1172/JCI106753.
5
[Resection of the small intestine].
Internist (Berl). 1975 Jun;16(6):260-6.
6
Bile acid-mediated postcholecystectomy diarrhea.胆汁酸介导的胆囊切除术后腹泻
Arch Intern Med. 1987 Jul;147(7):1327-9.
7
Effects of jejunoileal bypass on the enterohepatic circulation of bile acids, bacterial flora in the upper small intestine, and absorption of vitamin B12.空肠回肠旁路术对胆汁酸肝肠循环、小肠上段细菌菌群及维生素B12吸收的影响。
Metabolism. 1983 Dec;32(12):1133-41. doi: 10.1016/0026-0495(83)90060-4.
8
Intestinal shunt-operation in obesity. A comparison of three types of operation.肥胖症的肠道分流手术。三种手术方式的比较。
Scand J Gastroenterol. 1973;8(5):457-64.
9
Effect of distal enterectomy on cholesterol and bile salt levels in the rat.远端肠切除术对大鼠胆固醇和胆汁盐水平的影响。
Rev Esp Fisiol. 1986 Sep;42(3):289-94.
10
Management of complications following intestinal bypass for morbid obesity.病态肥胖肠道旁路术后并发症的管理
Mo Med. 1974 Mar;71(3):119-21 passim.

引用本文的文献

1
Surgical management of morbid obesity.病态肥胖的外科治疗
Gut. 1981 Mar;22(3):242-54. doi: 10.1136/gut.22.3.242.
2
Bile salt metabolism following jejunoileal bypass for morbid obesity.病态肥胖空肠回肠旁路术后的胆汁酸代谢
Ann Surg. 1977 Jan;185(1):67-72. doi: 10.1097/00000658-197701000-00011.
3
Short bowel syndrome following surgical correction of a double intussusception in a dog.一只狗在接受双重肠套叠手术矫正后出现短肠综合征。
Can Vet J. 1978 Sep;19(9):254-9.