Aeinehchi M, Eslami B, Ghanbariha M, Saffar A S
Department of Endodontics, Azad University School of Dentistry, Tehran, Iran.
Int Endod J. 2003 Mar;36(3):225-31. doi: 10.1046/j.1365-2591.2003.00652.x.
To compare mineral trioxide aggregate (MTA) with calcium hydroxide when used as pulp-capping materials in human teeth.
Eleven pairs of maxillary third molars in subjects between 20 and 25 years of age were subjected to mechanical pulp exposure. The exposed pulps were capped with MTA or calcium hydroxide, covered with ZOE and restored with amalgam. A total of 14 teeth were extracted after periods of 1 week (two molars) 2 months (three molars), 3 months (five molars), 4 months (two molars) and 6 months (two molars).
Histological evaluation demonstrated less inflammation, hyperaemia and necrosis plus thicker dentinal bridge and more frequent odontoblastic layer formation with MTA than calcium hydroxide.
Although the results favour the use of MTA, more studies with larger samples and a longer follow up are suggested.
比较无机三氧化物聚合体（MTA）与氢氧化钙作为人类牙齿盖髓材料的效果。
选取11对年龄在20至25岁之间受试者的上颌第三磨牙，进行机械性牙髓暴露。暴露的牙髓用MTA或氢氧化钙覆盖，再用氧化锌丁香油糊剂覆盖，并用汞合金修复。分别在1周（2颗磨牙）、2个月（3颗磨牙）、3个月（5颗磨牙）、4个月（2颗磨牙）和6个月（2颗磨牙）后，总共拔除14颗牙齿。
组织学评估显示，与氢氧化钙相比，MTA导致的炎症、充血和坏死更少，牙本质桥更厚，成牙本质细胞层形成更频繁。
尽管结果表明使用MTA效果更好，但建议进行更多样本量更大、随访时间更长的研究。
