Gao Yue, Hu Mina, Xu Jian
Department of Periodontology, Shaoxing Stomatological Hospital, Shaoxing City, China.
Department of Endodontics, Shaoxing Stomatological Hospital, Shaoxing City, China.
Acta Odontol Scand. 2025 Jun 10;84:332-340. doi: 10.2340/aos.v84.43804.
To systematically evaluate the efficacy of diode laser for pulpotomy in primary teeth using meta-analysis. Methods: Electronic databases (PubMed, Web of Science, Cochrane Library, and Embase) were systematically searched to include randomised controlled trials (RCTs) evaluating the efficacy of diode laser pulpotomy in primary teeth, with the control group receiving conventional treatment without diode laser. This meta-analysis was based on a systematic literature search. Meta-analyses were conducted based on different follow-up times and control groups to assess the clinical and radiographic success rates of diode laser pulpotomy. Results: A total of 17 RCTs met the inclusion criteria, involving 1,018 primary teeth. Meta-analysis results based on different follow-up times (≤ 3 months, 6 months, 9 months, ≥12 months) showed similar clinical success rates (total: relative risk [RR], 1.01; 95% confidence interval [CI], 0.99-1.03; I2 = 0%) and radiographic success rates (total: RR, 0.99; 95% CI, 0.97-1.02; I2 = 0%) between diode laser pulpotomy and conventional treatment. Meta-analysis based on different control groups (formocresol-zinc oxide eugenol [FC-ZOE], ferric sulfate-zinc oxide eugenol [FS-ZOE], mineral trioxide aggregate-zinc oxide eugenol [MTA-ZOE], simvastatin gel-resin modified glass ionomer cement [SG-REGIC]) showed similar clinical success rates between diode laser pulpotomy and FC-ZOE (RR: 1.00; 95% CI: 0.98-1.02), MTA-ZOE (RR: 1.01; 95% CI: 0.94-1.09), and SG-REGIC (RR: 0.99; 95% CI: 0.83-1.17), but it was more likely to achieve clinical success compared to FS-ZOE (RR: 1.04; 95% CI: 1.01-1.07). In addition, diode laser pulpotomy showed similar radiographic success rates with different control groups. Conclusion: Diode laser can be considered as an alternative treatment method to current conventional pulpotomy. However, further high-quality trials are needed to confirm the accuracy and reliability of these findings.
采用荟萃分析系统评价二极管激光在乳牙活髓切断术中的疗效。方法：系统检索电子数据库（PubMed、Web of Science、Cochrane图书馆和Embase），纳入评估二极管激光乳牙活髓切断术疗效的随机对照试验（RCT），对照组接受不使用二极管激光的传统治疗。本荟萃分析基于系统的文献检索。根据不同的随访时间和对照组进行荟萃分析，以评估二极管激光活髓切断术的临床和影像学成功率。结果：共有17项RCT符合纳入标准，涉及1018颗乳牙。基于不同随访时间（≤3个月、6个月、9个月、≥12个月）的荟萃分析结果显示，二极管激光活髓切断术与传统治疗的临床成功率相似（总计：相对危险度[RR]，1.01；95%置信区间[CI]，0.99 - 1.03；I² = 0%），影像学成功率也相似（总计：RR，0.99；95% CI，0.97 - 1.02；I² = 0%）。基于不同对照组（甲醛甲酚 - 氧化锌丁香酚[FC - ZOE]、硫酸铁 - 氧化锌丁香酚[FS - ZOE]、矿物三氧化物聚合体 - 氧化锌丁香酚[MTA - ZOE]、辛伐他汀凝胶 - 树脂改性玻璃离子水门汀[SG - REGIC]）的荟萃分析显示，二极管激光活髓切断术与FC - ZOE（RR：1.00；95% CI：0.98 - 1.02）、MTA - ZOE（RR：1.01；95% CI：0.94 - 1.09）和SG - REGIC（RR：0.99；95% CI：0.83 - 1.17）的临床成功率相似，但与FS - ZOE相比更有可能获得临床成功（RR：1.04；95% CI：1.01 - 1.07）。此外，二极管激光活髓切断术与不同对照组的影像学成功率相似。结论：二极管激光可被视为当前传统活髓切断术的替代治疗方法。然而，需要进一步的高质量试验来证实这些发现的准确性和可靠性。
