Akhtar M Nadeem, Choudhary M Iqbal, Sener Bilge, Erdogan Ilkay, Tsuda Yoshisuke
International Center for Chemical Sciences, H E J Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Phytochemistry. 2003 May;63(1):115-22. doi: 10.1016/s0031-9422(02)00569-1.
Two members of a new class of C-nor-D-homo steroidal alkaloids, impranine (1). and dihydroimpranine (2). along with a new pyridyl-pregnane-type steroidal alkaloid, fetisinine (3). and a known base, korsevine (4). were isolated from the bulbs of Fritillaria imperialis. The structures of the compounds were established on the basis of spectroscopic techniques and some chemical transformations. Compounds 1 and 2 form a new class of steroidal alkaloids, named as "impranane."
从帝王贝母的鳞茎中分离出了一类新型C-去甲-D-高甾体生物碱的两个成员，即英普瑞宁（1）和二氢英普瑞宁（2），以及一种新型吡啶基孕甾烷型甾体生物碱，费替西宁（3）和一种已知的碱，科尔西文（4）。这些化合物的结构是基于光谱技术和一些化学转化确定的。化合物1和2构成了一类新型的甾体生物碱，命名为“英普烷”。
