Lagarde Emmanuel, Guyavarch Emmanuelle, Piau Jean-Pierre, Gueye-Ndiaye Aïssatou, Seck Karim, Enel Catherine, Pison Gilles, Ndoye Ibrahima, Mboup Souleymane
Institut National de Santé et de la Recherche Médicale (INSERM), Unité 88, Saint-Maurice, Paris, France.
Int J STD AIDS. 2003 Mar;14(3):208-15. doi: 10.1258/095646203762869241.
A rural population of east Senegal has been under demographic surveillance for more than 30 years and a high rate of infertility has been reported. The aim of the study is to describe HIV and treponemal infection epidemiology and association with outcome of pregnancy in a population of rural Senegal. A population-based cross-sectional study was conducted among 952 randomly-selected adults of a rural community of Senegal. No participant was found to be infected with HIV, 11% had evidence of past syphilis and 5% of active syphilis. Active syphilis was associated among men with age, long-term mobility and having partners in an urban area in the last 12 months and among women with being divorced or widowed. No association was found between past or active syphilis and abortion or stillbirth but women aged 40 and more with past or active syphilis were significantly more likely to have had no history of gestation than women with no evidence of syphilis infection. In conclusion our results call for more research to understand the epidemiology of treponemal infection and to elucidate types of Treponema pallidum involved.
塞内加尔东部的一个农村人口已接受人口监测30多年，据报道不孕率很高。本研究的目的是描述塞内加尔农村人群中艾滋病毒和梅毒感染的流行病学情况及其与妊娠结局的关联。在塞内加尔一个农村社区随机抽取的952名成年人中开展了一项基于人群的横断面研究。未发现有参与者感染艾滋病毒，11%的人有既往梅毒感染证据，5%的人患有活动性梅毒。男性活动性梅毒与年龄、长期流动以及过去12个月内在城市地区有伴侣有关，女性则与离婚或丧偶有关。既往或活动性梅毒与流产或死产之间未发现关联，但40岁及以上有既往或活动性梅毒的女性比无梅毒感染证据的女性更有可能无妊娠史。总之，我们的研究结果呼吁开展更多研究，以了解梅毒感染的流行病学情况，并阐明所涉及的梅毒螺旋体类型。
