Christie K E, Solberg C O, Larsen B, Grov A, Tonder O
Acta Pathol Microbiol Scand C. 1976 Apr;84(2):119-23. doi: 10.1111/j.1699-0463.1976.tb00008.x.
The phagocytosis and intracellular killing of Staphylococcus aureus by humans granulocytes in the presence of immunoglobulin preparations have been examined. Isolated IgG from pooled human serum induced phagocytosis and intracellular killing of bacteria. F(ab')2 fragments had no significant effect, indicating that the Fc piece of the IgG molecule is of importance not only for the phagocytosis but also for the intracellular killing of bacteria. Isolated IgM stimulated the phagocytosis to a minor extent, with no enhancement of the bactericidal activity.
在免疫球蛋白制剂存在的情况下，对人类粒细胞吞噬和细胞内杀灭金黄色葡萄球菌的情况进行了研究。从混合人血清中分离出的IgG可诱导细菌的吞噬作用和细胞内杀灭。F(ab')2片段没有显著作用，这表明IgG分子的Fc片段不仅对吞噬作用很重要，而且对细菌的细胞内杀灭也很重要。分离出的IgM在一定程度上刺激了吞噬作用，但没有增强杀菌活性。
