Solberg C O, Christie K E, Larsen B, Tonder O
Acta Pathol Microbiol Scand C. 1976 Apr;84(2):112-8. doi: 10.1111/j.1699-0463.1976.tb00007.x.
The influence of serum natibodies and thermolabile serum factors on the intracellular killing of Staphylococcus aureus by neutrophil granulocytes has been examined using a method which facilitates a precise in vitro evaluation of the phagocytic and bactericidal activities of human polymorphonuclear leucocytes. The bactericidal activity of the granulocytes was significantly less pronounced in the presence of serum absorbed with Staph. aureus or inactivated at 56 degrees C for 30 minutes than in the presence of untreated serum. Specific antibodies seemed to stimulate the intracellular killing of bacteria more than thermolabile serum factors.
利用一种有助于精确体外评估人类多形核白细胞吞噬和杀菌活性的方法，研究了血清抗体和热不稳定血清因子对中性粒细胞对金黄色葡萄球菌细胞内杀伤作用的影响。与未处理的血清相比，在存在用金黄色葡萄球菌吸收的血清或在56℃灭活30分钟的血清时，粒细胞的杀菌活性明显较弱。特异性抗体似乎比热不稳定血清因子更能刺激细胞内对细菌的杀伤作用。
