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对酗酒者长达25年的随访研究显示,其患结直肠癌不存在额外风险。

No excess risk of colorectal cancer among alcoholics followed for up to 25 years.

作者信息

Ye W, Romelsjö A, Augustsson K, Adami H-O, Nyrén O

机构信息

Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden.

出版信息

Br J Cancer. 2003 Apr 7;88(7):1044-6. doi: 10.1038/sj.bjc.6600846.

DOI:10.1038/sj.bjc.6600846
PMID:12671702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2376377/
Abstract

We conducted a population-based retrospective cohort study among 179,398 Swedish patients hospitalised for alcoholism from 1970 to 1994, and found no excess risk for colorectal cancers, overall or at any anatomical subsite. Our findings challenge the hypothesis that alcohol intake is a risk factor for cancer of the large bowel.

摘要

我们对1970年至1994年间因酗酒住院的179398名瑞典患者进行了一项基于人群的回顾性队列研究,结果发现,无论是总体还是任何解剖亚部位,患结直肠癌的风险均未增加。我们的研究结果对酒精摄入是大肠癌症危险因素这一假设提出了质疑。

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本文引用的文献

1
Effects of alcohol consumption on the risk of colorectal cancer among men by anatomical subsite (Canada).饮酒对加拿大男性不同解剖部位结直肠癌风险的影响。
Cancer Causes Control. 2002 Jun;13(5):483-91. doi: 10.1023/a:1015700415808.
2
Risk of adenocarcinomas of the esophagus and gastric cardia in patients with gastroesophageal reflux diseases and after antireflux surgery.胃食管反流病患者及抗反流手术后食管腺癌和贲门腺癌的风险
Gastroenterology. 2001 Dec;121(6):1286-93. doi: 10.1053/gast.2001.29569.
3
An updated review of the epidemiological evidence that cigarette smoking increases risk of colorectal cancer.吸烟增加结直肠癌风险的流行病学证据的最新综述。
Cancer Epidemiol Biomarkers Prev. 2001 Jul;10(7):725-31.
4
Per capita alcohol consumption and liver cirrhosis mortality in 14 European countries.14个欧洲国家的人均酒精消费量与肝硬化死亡率
Addiction. 2001 Feb;96 Suppl 1:S19-33. doi: 10.1080/09652140020021152.
5
Nutritional status of folate and colon cancer risk: evidence from NHANES I epidemiologic follow-up study.叶酸营养状况与结肠癌风险:来自美国国家健康和营养检查调查I流行病学随访研究的证据。
Ann Epidemiol. 2001 Jan;11(1):65-72. doi: 10.1016/s1047-2797(00)00188-5.
6
Colorectal cancer: molecules and populations.结直肠癌:分子与群体
J Natl Cancer Inst. 1999 Jun 2;91(11):916-32. doi: 10.1093/jnci/91.11.916.
7
Cigarette smoking, alcohol use, and colorectal adenoma in Japanese men and women.日本男性和女性的吸烟、饮酒与结肠直肠腺瘤
Dis Colon Rectum. 1999 Mar;42(3):337-42. doi: 10.1007/BF02236350.
8
Alcohol and cancer.酒精与癌症。
Recent Dev Alcohol. 1998;14:67-95. doi: 10.1007/0-306-47148-5_4.
9
Alcohol, methylxanthine-containing beverages, and colorectal cancer in Córdoba, Argentina.阿根廷科尔多瓦的酒精、含甲基黄嘌呤饮料与结直肠癌
Eur J Cancer Prev. 1998 Jun;7(3):207-13. doi: 10.1097/00008469-199806000-00005.
10
Risk factors for colorectal cancer in a prospective study among U.S. white men.
Int J Cancer. 1998 Aug 12;77(4):549-53. doi: 10.1002/(sici)1097-0215(19980812)77:4<549::aid-ijc13>3.0.co;2-1.