Gragoudas E S, Chandra S R, Friedman E, Klein M L, Van Buskirk M
Arch Ophthalmol. 1976 May;94(5):755-7. doi: 10.1001/archopht.1976.03910030365003.
Of 84 patients with unilateral disciform macular degeneration, 36 were followed up for one to four years (average, 22 months). The fellow eye in 13 cases developed disciform lesions during that follow-up period. A significantly greater number of drusen were found in the fellow eyes of patients with unilateral disciform macular degeneration than in the eyes of a comparable control group of patients (P less than .001). Furthermore, the eyes with unilateral disciform macular degeneration that developed disciform lesions in the other eye were characterized as a group by a significantly larger number of drusen than those that did not. We postulate that drusen are precursors of disciform macular degeneration in fellow eyes and are probably manifestations of the same exudative process.
在84例单侧盘状黄斑变性患者中，36例随访了1至4年（平均22个月）。在该随访期间，13例患者的对侧眼出现了盘状病变。单侧盘状黄斑变性患者对侧眼中发现的玻璃膜疣数量明显多于可比对照组患者的眼睛（P小于0.001）。此外，在对侧眼出现盘状病变的单侧盘状黄斑变性眼组，其玻璃膜疣数量明显多于未出现病变的眼组。我们推测，玻璃膜疣是对侧眼盘状黄斑变性的先兆，可能是同一渗出过程的表现。
