Fraunfelder F T, Watson P G
Br J Ophthalmol. 1976 Mar;60(3):227-30. doi: 10.1136/bjo.60.3.227.
A series of 30 enucleated eyes, all of which had a primary histological diagnosis of scleritis, was analysed. The average age of patients at enucleation was 68 years; many of these patients had had the disease for more than 30 years. In 40 per cent the diagnosis of scleritis was unsuspected and was often masked by multiple complications. Scleritis with uveitis and glaucoma was the most common combination to come to enucleation. In 82 per cent, pain was the reason for enucleation, which suggests that some patients were on inadequate levels of steroid treatment or were unable to tolerate them. In the series, 37 per cent of the eyes perforated. Perforation occurred in those patients who were having steriods but not in those who were not, but the data are inconclusive as to which method of steroid administration was most likely to cause ocular perforation.
对一系列30只摘除眼球进行了分析，所有这些眼球的初步组织学诊断均为巩膜炎。摘除眼球时患者的平均年龄为68岁；这些患者中许多人患病已超过30年。40%的巩膜炎诊断未被怀疑，且常被多种并发症掩盖。伴有葡萄膜炎和青光眼的巩膜炎是最常见的导致眼球摘除的组合。82%的病例中，疼痛是摘除眼球的原因，这表明一些患者的类固醇治疗剂量不足或无法耐受。在该系列中，37%的眼球发生了穿孔。穿孔发生在正在使用类固醇的患者中，而非未使用类固醇的患者，但关于哪种类固醇给药方法最有可能导致眼球穿孔的数据尚无定论。
