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使用抗脂多糖单克隆抗体进行伯氏考克斯氏体的抗原分析。

Use of monoclonal antibodies to lipopolysaccharide for antigenic analysis of Coxiella burnetii.

作者信息

Hotta Akitoyo, Kawamura Midori, To Ho, Andoh Masako, Yamaguchi Tsuyoshi, Fukushi Hideto, Amano Ken-Ichi, Hirai Katsuya

机构信息

Department of Veterinary Microbiology, Faculty of Agriculture, Gifu University, 1-1 Yanagido, Gifu, Gifu 501-1193, Japan.

出版信息

J Clin Microbiol. 2003 Apr;41(4):1747-9. doi: 10.1128/JCM.41.4.1747-1749.2003.

Abstract

Antigenic differences among Coxiella burnetii strains were analyzed. The monoclonal antibodies against the lipopolysaccharide outer core did not react with the strains containing a QpRS plasmid or with plasmidless strains, whereas they reacted with strains containing a QpH1 or QpDV plasmid. C. burnetii isolates could be divided into two groups immunologically.

摘要

对伯纳特柯克斯体菌株之间的抗原差异进行了分析。针对脂多糖外核心的单克隆抗体不与含有QpRS质粒的菌株或无质粒菌株发生反应,而它们与含有QpH1或QpDV质粒的菌株发生反应。伯纳特柯克斯体分离株在免疫学上可分为两组。

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