Burke Emma R, Holden Alexis J, Shaw Ian C
Department of Environmental Management, University of Central Lancashire, Preston PR1 2HE, UK.
Chemosphere. 2003 Jan;50(4):529-35. doi: 10.1016/s0045-6535(02)00492-7.
A method has been developed for the analysis of organochlorine pesticides in human milk using solvent extraction, Florisil solid phase extraction clean-up and analysis by gas chromatography with an electron capture detector. The recovery of analytes from spiked milk samples was in the range 53 +/- 1% to 109 +/- 7% (n = 9). A small number of samples were obtained from women in a rural and an urban area of Indonesia and analysed using the developed method. The results are reported on a milk fat basis. All samples contained detectable residues of p,p'-DDT (urban mean 0.11 +/- 0.18 mgkg(-1) (n = 5), rural mean 0.07 +/- 0.03 mg kg(-1) (n = 5)) and p,p'-DDE (urban mean 0.05 +/- 0.04 m kg(-1) (n = 5), rural mean 0.76 +/- 1.46 mg kg(-1) (n = 5)). Residues of HCB, betaHCH, alpha-endosulfan and dieldrin were also detected in some samples. There was no significant difference (at the 95% confidence level) in levels of pesticides between urban and rural areas. The levels of organochlorine pesticides in milk from Indonesian women were lower than those reported from Indonesian women exposed to DDT through malaria eradication schemes and were similar to levels reported from UK and Japan.
已开发出一种方法，用于分析人乳中的有机氯农药，该方法采用溶剂萃取、弗罗里硅土固相萃取净化，并通过带有电子捕获检测器的气相色谱进行分析。加标牛奶样品中分析物的回收率在53±1%至109±7%之间（n = 9）。从印度尼西亚农村和城市地区的妇女那里获取了少量样品，并使用所开发的方法进行分析。结果以乳脂为基础进行报告。所有样品均含有可检测到的对，对'-滴滴涕残留（城市平均0.11±0.18 mgkg⁻¹（n = 5），农村平均0.07±0.03 mg kg⁻¹（n = 5））和对，对'-滴滴伊残留（城市平均0.05±0.04 m kg⁻¹（n = 5），农村平均0.76±1.46 mg kg⁻¹（n = 5））。在一些样品中还检测到六氯苯、β-六氯环己烷、α-硫丹和狄氏剂的残留。城乡地区农药水平之间没有显著差异（在95%置信水平）。印度尼西亚妇女乳汁中有机氯农药的水平低于通过疟疾根除计划接触滴滴涕的印度尼西亚妇女报告的水平，并且与英国和日本报告的水平相似。
