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对接受医学治疗的甲状腺功能减退患者的牙种植体研究。

A study of dental implants in medically treated hypothyroid patients.

作者信息

Attard Nikolai J, Zarb George A

机构信息

Faculty of Dentistry, University of Toronto, Ontario, Canada.

出版信息

Clin Implant Dent Relat Res. 2002;4(4):220-31. doi: 10.1111/j.1708-8208.2002.tb00174.x.

Abstract

PURPOSE

The purpose of this study was to investigate the success outcomes of implants and prosthodontic treatment placed in patients with a previous history of hypothyroidism that was being controlled with medications.

MATERIALS AND METHODS

Twenty-seven female patients with a medically confirmed history of primary hypothyroid disease who were on replacement medications at the time of implant surgery were selected as the study group. They were matched with 29 control patients by age, gender, location (jaw and zone) of implants, type of prosthesis, and dental status of the opposing arch. Additional factors studied were medical history, medications, smoking habits, and bone quality and quantity.

RESULTS

There was no statistical difference in the number of implant failures between the two groups (p = .781). The hypothyroid patients had more soft tissue complications (p = .018) following stage 1 surgery. More bone loss around implants in the hypothyroid patients was recorded after year 1 of loading when compared with loss in their matched controls (p = .017).

CONCLUSIONS

This study suggests that medically controlled hypothyroid female patients treated with dental implants are not at higher risk of implant failure when compared with matched controls, and that a history of controlled hypothyroidism does not appear to be a contraindication for implant therapy with endosseous implants.

摘要

目的

本研究旨在调查在有甲状腺功能减退病史且正在接受药物治疗的患者中植入种植体及进行修复治疗的成功结果。

材料与方法

选择27名经医学确诊有原发性甲状腺功能减退疾病史且在种植手术时正在接受替代药物治疗的女性患者作为研究组。根据年龄、性别、种植体植入位置(颌骨和区域)、修复体类型以及对颌牙列状况,将她们与29名对照患者进行匹配。研究的其他因素包括病史、药物治疗、吸烟习惯以及骨质量和骨量。

结果

两组之间种植体失败数量无统计学差异(p = 0.781)。甲状腺功能减退患者在一期手术后有更多软组织并发症(p = 0.018)。与匹配的对照患者相比,甲状腺功能减退患者在负重1年后种植体周围的骨吸收更多(p = 0.017)。

结论

本研究表明,与匹配的对照患者相比,接受药物治疗的甲状腺功能减退女性患者接受牙种植治疗时种植体失败风险并不更高,且甲状腺功能减退得到控制的病史似乎并非骨内种植体治疗的禁忌证。

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