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甲状腺疾病患者是牙种植的禁忌证吗?一项系统评价。

Patients with Thyroid Disorder, a Contraindication for Dental Implants? A Systematic Review.

作者信息

Torrejon-Moya Aina, Izquierdo-Gómez Keila, Pérez-Sayáns Mario, Jané-Salas Enric, Marí Roig Antonio, López-López José

机构信息

Department of Odontoestomatology, Faculty of Medicine and Health Sciences, School of Dentistry, University Campus of Bellvitge, University of Barcelona, 08907 Barcelona, Spain.

Oral Health and Masticatory System Group, IDIBELL (Bellvitge Biomedical Research Institute), University of Barcelona, 08907 Barcelona, Spain.

出版信息

J Clin Med. 2022 Apr 25;11(9):2399. doi: 10.3390/jcm11092399.

DOI:10.3390/jcm11092399
PMID:35566524
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9102443/
Abstract

The thyroid gland is composed of the thyroid follicles, considered to be the functional units of the thyroid gland. The synthesis of the thyroid hormones occurs in these follicles. Triiodothyronine (T3) and thyroxine (T4) are the thyroid hormones and affect metabolic processes all through the body. This systematic evaluation was performed to answer the following PICO question: "Can patients with thyroid disorders undergo dental implant rehabilitation with the same survival rate as patients without thyroid disorders?". A systematic review of the literature was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements to gather available and current evidence of thyroid disorders and its relationship with dental implants. The electronic search, in the PubMed and Cochrane databases, yielded 22 articles. Out of the 22 articles, only 11 fulfilled the inclusion criteria. Manual research of the reference list yielded no additional papers. According to the SORT criteria and answering our PICO question, level B can be established to conclude that patients with thyroid disorders can be rehabilitated with dental implants, with similar survival rates as patients without thyroid disorders. Papers with higher scientific evidence and bigger sample size should be carried out.

摘要

甲状腺由甲状腺滤泡组成,甲状腺滤泡被认为是甲状腺的功能单位。甲状腺激素的合成发生在这些滤泡中。三碘甲状腺原氨酸(T3)和甲状腺素(T4)是甲状腺激素,它们影响全身的代谢过程。进行这项系统评价是为了回答以下PICO问题:“甲状腺疾病患者能否像无甲状腺疾病的患者一样,以相同的存活率接受牙种植修复?”。按照系统评价和Meta分析的首选报告项目(PRISMA)声明对文献进行了系统回顾,以收集有关甲状腺疾病及其与牙种植体关系的现有和最新证据。在PubMed和Cochrane数据库中进行电子检索,共检索到22篇文章。在这22篇文章中,只有11篇符合纳入标准。对参考文献列表进行人工检索未发现其他文章。根据SORT标准并回答我们的PICO问题,可以确定为B级结论,即甲状腺疾病患者可以通过牙种植体进行修复,其存活率与无甲状腺疾病的患者相似。应开展具有更高科学证据和更大样本量的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c7/9102443/f5f3846d0510/jcm-11-02399-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c7/9102443/c9e2641cff60/jcm-11-02399-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c7/9102443/f5f3846d0510/jcm-11-02399-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c7/9102443/c9e2641cff60/jcm-11-02399-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c7/9102443/f5f3846d0510/jcm-11-02399-g002.jpg

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Materials (Basel). 2022 Feb 20;15(4):1582. doi: 10.3390/ma15041582.
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Int J Surg. 2021 Apr;88:105906. doi: 10.1016/j.ijsu.2021.105906. Epub 2021 Mar 29.
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