Lee Yuan-Chieh, Hu Fung-Rong, Wang I-Jong
Department of Ophthalmology, Tzu-Chi Buddhist General Hospital, Taipei, Taiwan.
J Cataract Refract Surg. 2003 Apr;29(4):769-77. doi: 10.1016/s0886-3350(02)01844-8.
To determine the influence of pupil size and the amount of ablation on visual performance and on the patient's perception of glare or halo after laser in situ keratomileusis (LASIK).
Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
This study included a random cross-section of 50 eyes of 32 patients with "uniform" topography at least 6 months after LASIK and 51 eyes of 28 patients who had normal corneas. Each LASIK patient completed a survey rating adverse effects such as symptoms of night glare and halo. Pupil diameter and best spectacle-corrected visual acuity (BSCVA) were measured under photopic and scotopic conditions. Contrast sensitivity was measured with an MCT 8000 (Vistech Consultants, Inc.) under daytime and nighttime and with night glare conditions. A Technomed C-scan (Technomed Technology) was performed, and the potential corneal visual acuity (PCVA) was calculated after the settings for the pupil size were changed to the values measured under bright-light or dim-light conditions.
No significant difference was found between the post-LASIK and normal cornea groups in photopic or scotopic BSCVA (P>.05). In cases of moderate myopia, the post-LASIK group had decreased PCVA and contrast sensitivity (P<.05). In cases of high myopia, the post-LASIK group had decreased contrast sensitivity at spatial frequencies of 1.5 cycles per degree (cpd) under daytime conditions and 3 cpd under nighttime conditions (P<.05). Glare or halo symptoms did not correlate with scotopic BSCVA, PCVA, or nighttime contrast sensitivity with or without glare (P>.05). Pupil size was not significantly correlated with glare or halo symptoms, BSCVA, or contrast sensitivity under scotopic or photopic conditions (P>.05). In moderate myopia, the amount of attempted correction of the spherical equivalent (SE) was correlated with halo symptoms (P<.05; adjusted r(2) = 0.17). In high myopia, the amount of attempted astigmatism correction was correlated with the development of glare symptoms (P<.05; adjusted r(2) = 0.16).
There was a decrease in contrast sensitivity in post-LASIK eyes. The amount of attempted correction of the SE or astigmatism was correlated with the development of glare and halo symptoms. Pupil size was not significantly correlated with glare or halo symptoms, BSCVA, or contrast sensitivity in post-LASIK patients with "uniform" topography who had scotopic pupils not larger than 7.0 mm.
确定瞳孔大小和切削量对准分子原位角膜磨镶术(LASIK)后视觉性能以及患者对眩光或光晕的感知的影响。
台湾台北国立台湾大学医院眼科。
本研究纳入了32例LASIK术后至少6个月且角膜地形图为“均匀”的患者的50只眼,以及28例角膜正常患者的51只眼,进行随机横断面研究。每位LASIK患者完成一项关于夜眩光和光晕等不良反应的问卷调查评分。在明视和暗视条件下测量瞳孔直径和最佳眼镜矫正视力(BSCVA)。使用MCT 8000(Vistech Consultants公司)在白天、夜间以及有夜间眩光的条件下测量对比敏感度。进行Technomed C扫描(Technomed Technology),在将瞳孔大小设置改为明视或暗视条件下测量的值后,计算潜在角膜视力(PCVA)。
LASIK术后组和正常角膜组在明视或暗视BSCVA方面未发现显著差异(P>0.05)。在中度近视病例中,LASIK术后组的PCVA和对比敏感度降低(P<0.05)。在高度近视病例中,LASIK术后组在白天条件下每度1.5周/度(cpd)以及夜间条件下3 cpd的空间频率时对比敏感度降低(P<0.05)。眩光或光晕症状与暗视BSCVA、PCVA或有无眩光时的夜间对比敏感度均无相关性(P>0.05)。瞳孔大小与暗视或明视条件下的眩光或光晕症状、BSCVA或对比敏感度均无显著相关性(P>0.05)。在中度近视中,等效球镜度(SE)的矫正量与光晕症状相关(P<0.05;调整后r(2)=0.17)。在高度近视中,散光矫正量与眩光症状的发生相关(P<0.05;调整后r(2)=0.16)。
LASIK术后眼的对比敏感度下降。SE或散光的矫正量与眩光和光晕症状的发生相关。对于角膜地形图“均匀”、暗视瞳孔不大于7.0 mm的LASIK术后患者,瞳孔大小与眩光或光晕症状、BSCVA或对比敏感度均无显著相关性。