Garcia M Lourdes, Huang David, Crowe Sue, Traboulsi Elias I
Department of Pediatric Ophthalmology and the Center for Genetic Eye Diseases, Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
J AAPOS. 2003 Feb;7(1):14-22. doi: 10.1067/mpa.2003.S1091853103000557.
To investigate a possible relationship between the slanting of palpebral fissures and the magnitude and axis of astigmatism in children with astigmatism.
Cross-sectional study at a referral center of 53 children with astigmatism of more than +1.50 D in at least 1 eye. Visual acuity testing, cycloplegic refraction, slit-lamp biomicroscopy, and ophthalmoscopy were done on every patient. Corneal topography was obtained in 40 cooperative patients. External photographs of the midface were taken in 45 children. The degree of slanting of the palpebral fissures was evaluated based on the photographs. The statistical analysis tool used was repeated measures analysis of variance. Patients in whom photographic analysis was not available were excluded from the part of the statistical analysis dealing with eyelid slant.
Palpebral fissure slant (P =.013) and gender (P =.0005) were highly correlated with the obliquity of cylinder axis. There was a possible correlation between gender and eyelid slant (P =.0594), with females having slightly larger degrees of upward palpebral fissure slanting and male more downward slanting of their fissures compared to published angles in an age-matched population. We found a statistically significant correlation between the degree of total astigmatism and a larger abnormal slant (P =.0192) and between the axis and magnitude of corneal astigmatism and abnormal slant (P =.0092). Higher degrees of eyelid slant (> 8 degrees or < -4 degrees ) increased the risk of high cylinder magnitude (> 3.00 D) by an odds ratio of 4.17 (95% CI: 1.03, 19.95).
Children with astigmatism with large degrees of slanting of their palpebral fissures are at higher risk for high astigmatism (> 3.00 D). The axis of the astigmatism is highly correlated with the slanting of the palpebral fissure.
研究散光患儿睑裂倾斜度与散光度数及轴位之间可能存在的关系。
在一家转诊中心对53例至少一只眼散光超过+1.50 D的儿童进行横断面研究。对每位患者进行视力测试、睫状肌麻痹验光、裂隙灯生物显微镜检查和检眼镜检查。40例配合的患者进行了角膜地形图检查。45例儿童拍摄了面部中部的外部照片。根据照片评估睑裂倾斜度。使用的统计分析工具是重复测量方差分析。无法进行照片分析的患者被排除在涉及眼睑倾斜度的统计分析部分。
睑裂倾斜度（P = 0.013）和性别（P = 0.0005）与柱镜轴位的倾斜度高度相关。性别与眼睑倾斜度之间可能存在相关性（P = 0.0594），与年龄匹配人群中公布的角度相比，女性睑裂向上倾斜度略大，男性睑裂向下倾斜度更大。我们发现总散光度数与较大的异常倾斜度之间存在统计学显著相关性（P = 0.0192），角膜散光的轴位和度数与异常倾斜度之间也存在相关性（P = 0.0092）。较高程度的眼睑倾斜（> 8度或< -4度）使高柱镜度数（> 3.00 D）的风险增加，优势比为4.17（95%可信区间：1.03, 19.95）。
睑裂倾斜度较大的散光患儿发生高度散光（> 3.00 D）的风险更高。散光轴位与睑裂倾斜度高度相关。
