Szczerbal I, Switonski M, Michalak E, Rogalska-Niznik N, Szamalek J, Schelling C
Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University, Poznán, Poland.
J Hered. 2003 Jan-Feb;94(1):107-10. doi: 10.1093/jhered/esg011.
Genes encoding keratins are evolutionary highly conserved and clustered in two linkage groups in mammalian genomes. Canine keratin 9 (K-9) and keratin 2e (K-2) cosmid-derived gene probes were used to localize the acidic and basic-neutral keratin gene clusters to cat chromosomes E1q12 and B4q15, respectively. The status of the physical map of the cat genome is discussed.
编码角蛋白的基因在进化上高度保守,并在哺乳动物基因组中聚集在两个连锁群中。犬角蛋白9(K-9)和角蛋白2e(K-2)黏粒衍生基因探针分别用于将酸性和碱性中性角蛋白基因簇定位到猫的E1q12和B4q15染色体上。文中讨论了猫基因组物理图谱的现状。