Ivanoff B, Chaignat C L
International Vaccine Institute, PO Box 14, Kwanak, Séoul, Corée.
Bull Soc Pathol Exot. 2002 Dec;95(5):355-8.
Cholera is still an important diarrhoeal disease in developing countries. The impact of cholera out-break is tremendous for a country at human and economic level. WHO estimates that diarrhoeal diseases cause about 2.8 million deaths per year in developing countries. Officially, cholera is causing around 120,000 deaths per year. The poorest population (from slums and refugee camps) are the most vulnerable target for cholera infection. Development of simple cheap and effective vaccine is highly recommended. This article aims at giving an update on the currently available and future vaccines for the prevention of diarrhoea due to Vibrio cholerae O1 and O139.
霍乱在发展中国家仍是一种重要的腹泻病。霍乱疫情对一个国家在人力和经济层面的影响是巨大的。世界卫生组织估计，腹泻病在发展中国家每年导致约280万人死亡。官方数据显示，霍乱每年造成约12万人死亡。最贫困人群（来自贫民窟和难民营）是霍乱感染最易受影响的目标群体。强烈建议研发简单、廉价且有效的疫苗。本文旨在介绍目前可用于预防霍乱弧菌O1和O139所致腹泻的疫苗以及未来的疫苗进展情况。
