Kim Seok Mo, Choi Ho Sun, Byun Ji Soo, Kim Yoon Ha, Kim Kyoung Seon, Rim So Yi, Kim Hyung Rok, Nam Jong Hee, Choi Yoo Duk
Department of Obstetrics and Gynaecology, Chonnam National University Medical School, Dongku, Gwangju, Korea.
J Obstet Gynaecol Res. 2003 Feb;29(1):28-32. doi: 10.1046/j.1341-8076.2003.00073.x.
Malignant transformation of mature cystic teratoma is an uncommon complication. While any of the constituent tissues of a teratoma has the potential to undergo malignant transformation, squamous cell carcinoma is the most commonly associated cancer. We present an unusual case of a postmenopausal woman with synchronous mucinous adenocarcinoma and strumal carcinoid tumor from one of two ovarian mature cystic teratomas (one in each ovary) with synchronous cervical cancer. We suggest that malignant transformation of mature cystic teratoma and synchronous cervical cancer be treated by hysterectomy, chemotherapy, and radiotherapy.
成熟囊性畸胎瘤的恶性转化是一种罕见的并发症。虽然畸胎瘤的任何组成组织都有可能发生恶性转化，但鳞状细胞癌是最常伴发的癌症。我们报告了一例不寻常的病例，一名绝经后女性，双侧卵巢成熟囊性畸胎瘤（每个卵巢各一个）中的一个发生了黏液腺癌和甲状腺肿类癌肿瘤，同时合并宫颈癌。我们建议成熟囊性畸胎瘤的恶性转化及同步性宫颈癌采用子宫切除术、化疗和放疗进行治疗。
