Department of Obstetrics and Gynecology, Iwaki Kyouritsu Hospital.
Department of Pathology, Iwaki Kyouritsu Hospital.
Fukushima J Med Sci. 2023 Apr 5;69(1):51-55. doi: 10.5387/fms.2022-22. Epub 2023 Mar 4.
Carcinoid tumors of the ovary are rare tumors, histopathologically classified as monodermal teratomas and somatic-type tumors arising from dermoid cysts. Their malignancy varies from borderline to malignant. Carcinoid tumors can occur in young and elderly women, and are sometimes seen in mature teratoma, struma ovarii, or mucinous cystadenoma as a nodule or tumor. Strumal carcinoid and mucinous carcinoid present as special types of carcinoid tumors of the ovary.
This report describes a 56-year-old woman who presented with a large pelvic mass on abdominal ultrasonography during a medical examination. The diameter of the pelvic tumor was approximately 11 cm and was suspected to be ovarian cancer. The values of CA125 and CEA were above their reference intervals on preoperative examination. Abdominal total hysterectomy and bilateral salpingo-oophorectomy were performed. Intraoperative frozen-section histopathology suggested a diagnosis of mucinous adenocarcinoma; therefore, partial omentectomy and pelvic lymphadenectomy were also performed. Permanent-section histopathology led to a final diagnosis of strumal carcinoid of the ovary, stage IA (FIGO 2014). Six years post-operation, the patient had no sign of recurrence.
卵巢类癌肿瘤是罕见的肿瘤，组织病理学上分类为单胚层畸胎瘤和来自皮样囊肿的体瘤。其恶性程度从交界性到恶性不等。类癌肿瘤可发生在年轻和老年妇女中，有时也可见于成熟畸胎瘤、卵巢甲状腺肿或黏液性囊腺瘤中作为结节或肿瘤。甲状腺肿型类癌和黏液性类癌是卵巢类癌的特殊类型。
本报告描述了一位 56 岁女性，在体检时腹部超声检查发现盆腔内有一个大肿块。盆腔肿瘤的直径约为 11 厘米，疑似卵巢癌。术前检查 CA125 和 CEA 的值均高于参考区间。行全子宫及双侧附件切除术。术中冷冻切片组织病理学提示诊断为黏液性腺癌；因此，还进行了部分网膜切除术和盆腔淋巴结切除术。石蜡切片组织病理学最终诊断为卵巢甲状腺肿型类癌，IA 期（FIGO 2014）。术后 6 年，患者无复发迹象。
