Jäger M, Jonas J B
Department of Ophthalmology, Eye Hospital, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Mannheim, Germany.
Eur J Ophthalmol. 2003 Mar;13(2):221-2. doi: 10.1177/112067210301300219.
To describe the occurrence of cystoid macular edema in a pseudophakic vitrectomized patient following use of latanoprost (0.005%).
A 58-year-old patient underwent routine cataract surgery with posterior chamber lens implantation complicated by rhegmatogenous retinal detachment three months later. A pars plana vitrectomy was performed with silicone oil endotamponade which was removed six months later. Five months after oil removal, the patient presented with secondary open-angle glaucoma treated with latanoprost 0.005% eye drops once daily.
Two weeks after initiation of latanoprost treatment, visual acuity dropped from 0.8 to 0.3 due to cystoid macular edema confirmed by fluorescein angiography. After discontinuing latanoprost therapy and with topical corticosteroid treatment, cystoid macular edema slowly resolved, and within 6 months, visual acuity improved to 0.8.
Despite its marked ocular hypotensive effect, latanoprost should be carefully used in patients after uncomplicated cataract surgery if the vitreous body was removed by pars piana vitrectomy.
描述一名行晶状体置换及玻璃体切割术的患者使用0.005%拉坦前列素后发生黄斑囊样水肿的情况。
一名58岁患者接受了常规白内障手术并植入后房型人工晶状体，3个月后并发孔源性视网膜脱离。行玻璃体切除术并硅油填充，6个月后取出硅油。取出硅油5个月后，患者出现继发性开角型青光眼，开始使用0.005%拉坦前列素滴眼液每日一次进行治疗。
拉坦前列素治疗2周后，视力从0.8降至0.3，荧光素血管造影证实为黄斑囊样水肿。停用拉坦前列素治疗并给予局部糖皮质激素治疗后，黄斑囊样水肿逐渐消退，6个月内视力恢复至0.8。
尽管拉坦前列素有显著的降眼压作用，但对于行单纯白内障手术且已通过平坦部玻璃体切除术切除玻璃体的患者，使用时应谨慎。
