Ayyala R S, Cruz D A, Margo C E, Harman L E, Pautler S E, Misch D M, Mines J A, Richards D W
Department of Ophthalmology, University of South Florida, Tampa, USA.
Am J Ophthalmol. 1998 Oct;126(4):602-4. doi: 10.1016/s0002-9394(98)00127-5.
To describe four patients who developed cystoid macular edema shortly after onset of treatment with latanoprost.
Retrospective review of medical records of patients with open-angle glaucoma who developed cystoid macular edema shortly after starting latanoprost.
The use of topical latanoprost was temporally related to the development of cystoid macular edema in four patients (six eyes; two aphakic eyes and four pseudophakic eyes). Cystoid macular edema resolved in all patients after latanoprost was discontinued.
Cystoid macular edema is a potential complication of latanoprost therapy. Further observations are needed to determine if the risk of cystoid macular edema is limited to or greatest in patients who are pseudophakic or aphakic.
描述四名在用拉坦前列素治疗后不久发生黄斑囊样水肿的患者。
对开角型青光眼患者在开始使用拉坦前列素后不久发生黄斑囊样水肿的病历进行回顾性研究。
四名患者(六只眼;两只无晶状体眼和四只人工晶状体眼)使用局部拉坦前列素与黄斑囊样水肿的发生在时间上相关。停用拉坦前列素后,所有患者的黄斑囊样水肿均消退。
黄斑囊样水肿是拉坦前列素治疗的潜在并发症。需要进一步观察以确定黄斑囊样水肿的风险是否仅限于无晶状体或人工晶状体患者,还是在这些患者中风险最大。