Nugent F W, Mallari R, George H, Ridley N
Gastroenterology. 1976 Jun;70(6):1014-6.
Serum lysozyme (muramidase) concentrations were measured in three groups of patients: control, ulcerative colitis and proctitis, and Crohn's disease. The mean +/-SD for each group was: control, 7 +/- 2; ulcerative colitis and proctitis, 7 +/- 2; and Crohn's disease, 10 +/- 4. Although a significant difference was seen between values in patients with Crohn's disease and values observed in those with ulcerative colitis or control patients, an important overlap was found between these groups. Further studies are necessary to explain the disparate results between this study and previous reports.
对三组患者测定了血清溶菌酶(胞壁质酶)浓度:对照组、溃疡性结肠炎和直肠炎组以及克罗恩病组。每组的均值±标准差分别为:对照组,7±2;溃疡性结肠炎和直肠炎组,7±2;克罗恩病组,10±4。虽然克罗恩病患者的值与溃疡性结肠炎患者或对照组患者的值之间存在显著差异,但在这些组之间发现了重要的重叠。需要进一步研究来解释本研究与先前报告之间不同的结果。