Leendertz Fabian H, Boesch Christophe, Junglen Sandra, Pauli Georg, Ellerbrok Heinz
Retrovirology, Robert Koch Institut, Berlin, Germany.
AIDS Res Hum Retroviruses. 2003 Mar;19(3):255-8. doi: 10.1089/088922203763315768.
A new strain of simian T-lymphotropic virus type 1 in blood samples from a chimpanzee that lived in the tropical rainforest of Ivory Coast is described. The sequence obtained from the long terminal repeat region of the genome is significantly divergent from all known human and nonhuman primate T-lymphotropic virus type 1 strains (963% homology to the closest related strains from Central African subtype B) and clusters with none of the established clades. The tax sequences reveal two sequence differences that seem to be unique as they are not found in any of the HTLV-1 or STLV-1 tax sequences from the public databases.
描述了从一只生活在象牙海岸热带雨林的黑猩猩血液样本中分离出的一种新型1型猿猴嗜T淋巴细胞病毒。从该病毒基因组的长末端重复区域获得的序列与所有已知的人类和非人灵长类动物1型嗜T淋巴细胞病毒毒株存在显著差异（与来自中非B亚型的最密切相关毒株的同源性为96.3%），并且不与任何已确定的进化枝聚类。tax序列显示出两个序列差异，这些差异似乎是独特的，因为在公共数据库中任何HTLV-1或STLV-1的tax序列中都未发现。
