在科特迪瓦伊塔伊国家公园的黑猩猩（Pan troglodytes verus）中存在多种不同的1型猿猴T细胞白血病病毒毒株。
High variety of different simian T-cell leukemia virus type 1 strains in chimpanzees (Pan troglodytes verus) of the Taï National Park, Côte d'Ivoire.
作者信息
Leendertz Fabian H, Junglen Sandra, Boesch Christophe, Formenty Pierre, Couacy-Hymann Emmanuel, Courgnaud Valerie, Pauli Georg, Ellerbrok Heinz
机构信息
Division of Retrovirology, Robert Koch Institute, D-13353 Berlin, Germany.
出版信息
J Virol. 2004 Apr;78(8):4352-6. doi: 10.1128/jvi.78.8.4352-4356.2004.
Abstract
We found human T-cell leukemia virus type 1- and simian T-cell leukemia virus type 1 (STLV-1)-related infections in 5 of 10 chimpanzees originating from three groups of wild chimpanzees. The new virus isolates showed a surprising heterogeneity not only in comparison to STLV-1 described previously in other primate species but also between the different chimpanzee groups, within a group, or even between strains isolated from an individual animal. The interdisciplinary combination of virology, molecular epidemiology, and long-term behavioral studies suggests that the primary route of infection might be interspecies transmission from other primates, such as red colobus monkeys, that are hunted and consumed by chimpanzees.
摘要
我们在来自三组野生黑猩猩的10只黑猩猩中，发现了5只感染了与人类1型嗜T细胞病毒和猴1型嗜T细胞病毒（STLV-1）相关的病毒。这些新的病毒分离株不仅与先前在其他灵长类物种中描述的STLV-1相比表现出惊人的异质性，而且在不同黑猩猩群体之间、群体内部，甚至从单个动物分离出的毒株之间也存在异质性。病毒学、分子流行病学和长期行为研究的跨学科结合表明，主要感染途径可能是来自其他灵长类动物的种间传播，比如被黑猩猩捕食并食用的红疣猴。
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