Eggermont Jos J, Ponton Curtis W
Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada.
Acta Otolaryngol. 2003 Jan;123(2):249-52. doi: 10.1080/0036554021000028098.
Human auditory system maturation as assessed by means of auditory-evoked potential recording is compared to maturation of axon neurofilaments and some critical stages in speech perception. The parallels strongly suggest that the emergence of the N1 component reflects the maturation of the axons in layer II and upper layer III of the auditory cortex. This is also the time period during which the perception of speech in noise and degraded speech markedly improves. The absence of N1 in cochlear implant subjects who have been deaf for a period of at least 3 years below the age of 6 years suggests a critical period in the maturation of the upper cortical layers and potentially poor future performance in the perception of masked and degraded speech.
通过听觉诱发电位记录评估的人类听觉系统成熟度，与轴突神经丝的成熟度以及言语感知中的一些关键阶段进行了比较。这些相似之处有力地表明，N1成分的出现反映了听觉皮层第二层和第三层上层轴突的成熟。这也是噪声中言语和 degraded speech（此处原文可能有误，推测为“退化言语”）感知显著改善的时间段。在6岁以下至少失聪3年的人工耳蜗植入受试者中未出现N1，这表明上层皮质层成熟存在关键期，并且在掩蔽和退化言语感知方面未来可能表现不佳。
