Gregory Patricia C, Kuhlemeier Keith V
Department of Physical Medicine and Rehabilitation, The John Hopkins University School of Medicine, Baltimore, MD 21239, USA.
Am J Phys Med Rehabil. 2003 May;82(5):364-9. doi: 10.1097/01.PHM.0000064725.62897.A5.
Deep venous thromboembolism (DVT) is an important health issue in the hospitalized geriatric population that leads to increased length of stay, morbidity, and mortality. Patients with hemorrhagic strokes are usually not placed on prophylactic therapy because of the risk of hemorrhagic extension of the stroke. The purpose of this study was to evaluate the prevalence of DVTs in hospitalized patients with hemorrhagic vs. thromboembolic strokes.
Retrospective chart review of data obtained from the Maryland Health Services Cost Review Commission data base for 1999 to determine the prevalence of DVTs in both hemorrhagic and thromboembolic stroke patients hospitalized acutely. Multiple logistic regression was performed to evaluate possible risk factors.
There were 1926 patients hospitalized with a primary diagnosis of hemorrhagic stroke and 15599 with thromboembolic stroke. Women in general had more strokes than men did. Older patients were more likely to have strokes as evidenced by the mean ages of 66 and 71 yr for hemorrhagic and thromboembolic strokes, respectively. A total of 37 patients (1.9%) with hemorrhagic strokes had DVTs, whereas 74 patients (0.5%) with thromboembolic strokes had DVTs. Hemorrhagic stroke was an independent risk factor for DVT (odds ratio, 2.60; 95% confidence interval, 1.49-4.55; P = 0.0008).
DVT prevalence and risk was higher among patients with hemorrhagic strokes in comparison with patients with thromboembolic strokes.
深静脉血栓形成(DVT)是老年住院患者中的一个重要健康问题,会导致住院时间延长、发病率和死亡率增加。出血性中风患者通常不进行预防性治疗,因为存在中风出血性扩展的风险。本研究的目的是评估出血性中风与血栓栓塞性中风住院患者中DVT的患病率。
对从马里兰州医疗服务成本审查委员会数据库获取的1999年数据进行回顾性图表审查,以确定急性住院的出血性和血栓栓塞性中风患者中DVT的患病率。进行多因素逻辑回归分析以评估可能的危险因素。
有1926例患者以出血性中风为主要诊断住院,15599例以血栓栓塞性中风住院。总体而言,女性中风患者比男性多。老年患者更容易发生中风,出血性和血栓栓塞性中风的平均年龄分别为66岁和71岁,这证明了这一点。共有37例(1.9%)出血性中风患者发生DVT,而74例(0.5%)血栓栓塞性中风患者发生DVT。出血性中风是DVT的独立危险因素(比值比,2.60;95%置信区间,1.49 - 4.55;P = 0.0008)。
与血栓栓塞性中风患者相比,出血性中风患者的DVT患病率和风险更高。